Omeros Corporation: A Comprehensive Guide to Understanding Its Uses, Dosage, Side Effects, Interactions, Generics, and Demographics Omeros Corporation is a biopharmaceutical company that focuses on the discovery, development, and commercialization of small-molecule and protein therapeutics for large unmet medical needs. The company is headquartered in Seattle, Washington, and was founded in 1994. This article will provide you with a comprehensive guide to understanding Omeros Corporation, covering its uses, dosage, side effects, interactions, generics, and demographics. We will take a closer look at the company's flagship product, Omidria (phenylephrine and ketorolac intraocular solution), to help you better understand the drug and its effects on patients. Uses Omeros Corporation's Omidria is an FDA-approved drug that is used during cataract surgery or intraocular lens replacement (IOL) to maintain pupil size, reduce postoperative pain, and prevent intraoperative miosis (constriction of the pupil). Specifically, Omidria is a combination of phenylephrine and ketorolac and is administered as an intraocular solution through a cannula in the eye. Dosage Omidria is usually administered by a healthcare professional during cataract surgery or IOL replacement. The recommended dosage for Omidria is 1 mL of the solution, which should be administered using a disposable cannula that is inserted through the side port incision or main incision created during surgery. The solution should be injected intraocularly approximately 5 to 20 minutes before the start of surgery and redosed as needed. Side Effects Like all medications, Omidria can cause side effects. The most common side effects of Omidria include eye irritation, eye redness, inflammation, and pupillary block. Additional potential side effects of the drug include headache, nausea, vomiting, and hypertension. Interactions Before undergoing cataract surgery or IOL replacement, it is important to disclose all medications you are taking, including vitamins, supplements, and over-the-counter medications. Omidria can interact with other drugs which may affect its effectiveness or cause adverse reactions. Specifically, Omidria should not be used concomitantly with other intraocular drugs that may affect pupil size or the dilation of the eye. Generics Currently, there are no generic versions of Omidria available on the market. However, the company has reported that it is planning to develop and market a generic version of the drug in the future. Demographics Omidria is indicated for use in adults during cataract surgery or IOL replacement. According to clinical trial data, the drug has been shown to be effective in both genders, as well as in patients of various age ranges and ethnic groups. However, it is important to note that Omidria has not been studied in pediatric patients. Conclusion Overall, Omeros Corporation's Omidria is an FDA-approved drug that is used during cataract surgery or IOL replacement to maintain pupil size, reduce postoperative pain, and prevent intraoperative miosis. The recommended dosage for the drug is 1 mL, and it should be administered by a healthcare professional using a disposable cannula. While Omidria can cause side effects, it has been shown to be effective in adults of various age ranges and ethnic groups. Currently, there are no generic versions of the drug available on the market, although the company has reported plans to develop and market a generic version in the future. Before undergoing cataract surgery or IOL replacement, it is important to disclose all medications you are taking to ensure that Omidria will be safe and effective for you.