Kaleo, Inc. is a pharmaceutical company that develops medical products and devices to improve and protect patient health. The company is focused on providing innovative solutions to improve access to medication for emergency conditions and chronic diseases. The company is best known for developing the Auvi-Q® epinephrine auto-injector, which delivers a precise dose of epinephrine in the event of a severe allergic reaction.
Uses
Kaleo's product portfolio includes a range of innovative medical solutions. The company's flagship product, the Auvi-Q® epinephrine auto-injector, is used in the treatment of severe allergic reactions, also known as anaphylaxis. The auto-injector delivers a precise dose of medication to patients experiencing anaphylaxis in a matter of seconds, reducing the risk of potentially life-threatening complications.
In addition to the Auvi-Q® epinephrine auto-injector, Kaleo also produces the EVZIO® Naloxone auto-injector, which is used in the treatment of opioid overdose. The auto-injector delivers a dose of naloxone, reversing the effects of opioids, and helping to restore normal respiratory function in patients.
Dosage
The dosage of each of Kaleo's products is unique and is based on the patient's age, weight, and medical history. For the Auvi-Q® epinephrine auto-injector, the device comes in two different doses: 0.1mg for patients who weigh between 7.5 and 25 kilograms, and 0.3mg for patients who weigh over 25 kilograms.
For the EVZIO® Naloxone auto-injector, the recommended dose is 2mg/0.4mL, administered intramuscularly or subcutaneously. The auto-injector comes with a voice-prompt system that guides the user through the administration process.
Side Effects
While Kaleo's products are generally well-tolerated, they may cause side effects in some patients. The most common side effects associated with the Auvi-Q® epinephrine auto-injector include anxiety, tremors, dizziness, sweating, and palpitations. These side effects are usually mild and short-lived. However, in some cases, patients may experience more serious side effects, such as irregular heart rhythm, high blood pressure, and cardiac arrest.
The most common side effects associated with the EVZIO® Naloxone auto-injector include headache, dizziness, nausea, and vomiting. In some cases, patients may experience more serious side effects, such as seizures, respiratory depression, and cardiac arrest. Patients should contact a healthcare provider immediately if they experience any unusual or severe side effects.
Interactions
Kaleo's products may interact with other medications or substances, which can affect their efficacy or safety. Patients should inform their healthcare provider if they are taking any other medications, supplements, or beverages before using Kaleo's products.
For instance, the Auvi-Q® epinephrine auto-injector may interact with beta-blockers, which can reduce the effectiveness of epinephrine. Patients should avoid using the auto-injector if they are taking beta-blockers, unless instructed otherwise by a healthcare provider.
The EVZIO® Naloxone auto-injector may interact with other opioids, which can reduce the effectiveness of naloxone. Patients should be careful when using the auto-injector alongside other opioids, and should only use the product as directed by a healthcare provider.
Generic
Kaleo's products are not available as generics, as they are protected by patents. However, the company offers a patient support program to help eligible patients access its products at a reduced cost.
Demographic
Kaleo's products are recommended for use in adults and children. However, the recommended dose may vary depending on the patient's age, weight, and medical history. Before using any of Kaleo's products, patients should consult with a healthcare provider to determine the appropriate dose and administration method.
In conclusion, Kaleo, Inc. is a pharmaceutical company that is dedicated to improving patient health by providing innovative medical solutions. The company's products, including the Auvi-Q® epinephrine auto-injector and the EVZIO® Naloxone auto-injector, are designed to treat severe allergic reactions and opioid overdoses respectively. Patients should consult with their healthcare provider before using any of Kaleo's products to determine the appropriate use, dosage, and potential side effects.