Corcept Therapeutics is a pharmaceutical company that focuses on developing medications to treat serious health conditions such as cancer, endocrine disorders, and psychiatric disorders. The company's flagship product, Korlym (mifepristone), is an FDA-approved medication used to treat Cushing's syndrome. In this article, we will cover the uses, dosage, side effects, interactions, generic, and demographic of Corcept Therapeutics and its flagship product Korlym. Uses Korlym is an oral medication used to treat Cushing's syndrome, a rare disorder caused by the excessive production of cortisol. Cortisol is a hormone produced by the adrenal glands that is important in regulating the body's response to stress. However, excessive levels of cortisol can cause a wide range of health problems such as high blood pressure, obesity, diabetes, and bone loss. Korlym works by blocking the cortisol receptors in the body, which decreases the amount of cortisol production. This medication has been shown to effectively reduce the symptoms of Cushing's syndrome such as abdominal fat, high blood pressure, and glucose intolerance. Dosage The recommended starting dose of Korlym is 300 mg per day, taken in a single oral dose. This medication should be taken with a meal. The dosage can be increased to 600 mg per day if the initial response is inadequate. The maximum recommended dose of Korlym is 1200 mg per day. Side Effects Like all medications, Korlym can cause side effects. The most common side effects reported with Korlym use include nausea, vomiting, headache, fatigue, and high blood pressure. Other less common side effects include dizziness, increased appetite, and low cortisol levels. In rare cases, Korlym can cause liver damage, which can be life-threatening. Interactions Korlym can interact with other medications. It is important to tell your doctor about all medications, supplements, and herbal products you are taking before starting Korlym. Korlym can reduce the effectiveness of hormonal contraceptives, so women who are taking hormonal contraceptives should use a backup form of contraception while taking Korlym. Generic As of now, there is no generic version available for Korlym. However, Corcept Therapeutics is actively working on developing a generic version of Korlym that will be more affordable for patients. Demographic Cushing's syndrome is a rare disorder that affects approximately 10-15 people per million each year. The condition can affect people of any age, but it most commonly affects women between the ages of 20 and 50. Cushing's syndrome can be caused by a variety of factors, including pituitary tumors, adrenal tumors, and long-term use of corticosteroids. Conclusion Corcept Therapeutics is a pharmaceutical company that is focused on developing medications to treat serious health conditions such as Cushing's syndrome. Korlym is the company's flagship product and is an FDA-approved medication used to treat Cushing's syndrome. Korlym works by blocking the cortisol receptors in the body, which decreases the amount of cortisol production, effectively reducing the symptoms of Cushing's syndrome. While Korlym can cause side effects, it has been shown to be an effective treatment for Cushing's syndrome. If you have Cushing's syndrome, talk to your doctor to see if Korlym is right for you.