ZILEUTON EXTENDED-RELEASE - ORAL

ZILEUTON EXTENDED-RELEASE - ORAL

PHONETIC PRONUNCIATION: (zye-LOO-ton)

COMMON BRAND NAME(S): Zyflo CR

GENERIC NAME(S): zileuton

Uses

USES: Zileuton is used to control and prevent symptoms (such as wheezing and shortness of breath) caused by asthma. Controlling symptoms of asthma helps you maintain your normal activities and cuts down on time lost from work or school. This medication must be used regularly to be effective. It does not work right away and should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (such as albuterol, salbutamol) as prescribed. This drug is not recommended for use in children younger than 12 years due to possible risk of liver problems.


How to use ZILEUTON EXTENDED-RELEASE - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking zileuton and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with food as directed by your doctor, usually 2 times daily (within 1 hour after the morning and evening meal). Swallow the tablets whole. Do not crush, chew, or split the tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Keep taking this medication even if you feel well. Do not increase your dose, use this drug more often, or stop using it without first consulting your doctor. Get medical help right away if your asthma symptoms worsen or if you are using your quick-relief inhaler more than usual or more often than prescribed.

Side Effects

SIDE EFFECTS: Nausea or diarrhea may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: symptoms of liver disease (such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine), mental/mood changes (such as trouble sleeping, agitation, hallucinations, depression, thoughts of suicide). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking zileuton, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, alcohol use. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older women may be at greater risk for liver problems while using this drug. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. This medication can slow down the removal of other medications from your body, which may affect how they work. An example of an affected drug is pimozide, among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

ZYFLO CR 600 MG TABLET

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ZILEUTON ER 600 MG TABLET

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red
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CT2

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Faq for ZILEUTON EXTENDED-RELEASE - ORAL

Zileuton Extended-Release is an oral medication used to treat asthma. It belongs to a class of drugs called leukotriene inhibitors.

Zileuton Extended-Release works by inhibiting the production of leukotrienes, substances in the body that cause inflammation and constriction of the airways in individuals with asthma.

The recommended dosage of Zileuton Extended-Release is typically 600 mg taken twice daily, approximately 12 hours apart. However, the dosage may vary depending on the individual and their response to the medication. It is important to follow the instructions provided by your healthcare provider.

Zileuton Extended-Release may start working within a few days of starting the medication. However, it may take several weeks to experience the full benefits. It is important to continue taking the medication as prescribed, even if you do not notice immediate improvements.

Common side effects of Zileuton Extended-Release include headache, trouble sleeping, upset stomach, nausea, liver function abnormalities, and rash. It is important to inform your healthcare provider if you experience any severe or persistent side effects.

Zileuton Extended-Release is not recommended for use in children under 12 years of age. The safety and effectiveness of the medication have not been established in this age group.

It is important to consult with your healthcare provider before using Zileuton Extended-Release during pregnancy or breastfeeding. The effects of the medication on unborn babies or nursing infants are not well-known, and the potential benefits and risks should be assessed.

Zileuton Extended-Release may interact with certain medications, such as theophylline, warfarin, and other drugs that are metabolized by the liver. It is important to inform your healthcare provider about any medications or supplements you are taking to avoid potential interactions.

Zileuton Extended-Release should be stored at room temperature, away from moisture and heat. It is important to keep the medication out of reach of children.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.