USTEKINUMAB - INJECTION

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USTEKINUMAB - INJECTION

PHONETIC PRONUNCIATION: (US-te-KIN-ue-mab)

COMMON BRAND NAME(S): Stelara

GENERIC NAME(S): ustekinumab

Uses

USES: Ustekinumab is used to treat plaque psoriasis, a certain type of arthritis (psoriatic arthritis), or a certain bowel condition (Crohn's disease). It works by blocking certain natural proteins in your body (interleukin-12 and interleukin-23) that cause inflammation (swelling) in these conditions. Ustekinumab does not cure these diseases, but helps to lessen symptoms of the disease. It can help to decrease the amount of plaques in plaque psoriasis, decrease the number of swollen/painful joints in psoriatic arthritis, and decrease symptoms such as abdominal pain/cramping and diarrhea in Crohn's disease.


How to use USTEKINUMAB - INJECTION

HOW TO USE: Read the Medication Guide and the Instructions for Use provided by your pharmacist before you start using ustekinumab and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Before starting this drug, you should take a tuberculosis (TB) skin test to check for a type of tuberculosis that may not be causing any symptoms (latent TB). If you are diagnosed with TB, to prevent a serious TB infection you must first be treated for it before you start ustekinumab. For the treatment of psoriasis or psoriatic arthritis, this medication is given by injection under your skin as directed by your doctor. You will receive one dose, followed by a second dose 4 weeks later. Then this medication is given every 3 months. For the treatment of Crohn's disease, the first dose of this medication is given by injection into a vein by a health care professional. The medication is then given by injection under your skin every 8 weeks as directed by your doctor. The dosage is based on your weight, medical condition, and response to treatment. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Do not shake the solution. The solution is normally colorless to light yellow. It may contain a few small white particles of protein. Before using, check this product visually for other particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Do not reuse syringes. When given under the skin, this medication should be injected in either the upper arms, buttock, thighs, or abdomen. It is important to change the location of the injection site with each dose to avoid problem areas under the skin. Therefore, choose a different injection site with each dose. Do not inject into skin that is irritated, sore, or infected. Use this medication regularly to get the most benefit from it. It may help to mark your calendar with a reminder. Tell your doctor if your condition does not improve or if it worsens.

Side Effects

SIDE EFFECTS: Bruising, itching, pain, redness, swelling, or hardening of the skin at the injection site may occur. Injection site reactions usually go away after 1 or 2 days. Headache, back pain, or sinus/throat pain may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: cough that doesn't go away, shortness of breath. This medication can affect your immune system. It can lower your body's ability to fight an infection. You may be more likely to get serious infections, such as lung infections, bone/joint infections, skin infections, sinus infections, or bowel/gallbladder infections. It may also be harder to fight an infection you already have. Tell your doctor right away if you develop any signs of an infection, such as worsening redness/swelling/tenderness at the injection site after 2 days, fever/chills, cold/flu symptoms, painful/frequent urination, unusual vaginal discharge/burning/itching/odor, severe stomach pain, or persistent nausea/vomiting. (See also Precautions section.) Ustekinumab may cause a rare (sometimes fatal) condition called RPLS (reversible posterior leukoencephalopathy syndrome). Get medical help right away if you develop persistent headache, seizures, sudden vision changes, mental/mood changes (such as confusion). There is a rare risk of developing cancer (including skin cancer) due to this medication. Discuss the risks and benefits of treatment with your doctor. Tell your doctor right away if you develop symptoms such as unusual lumps/growths, unusual skin changes (including a sore that does not heal or a change in the size/shape/color of a mole), swollen glands, unexplained weight loss. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using ustekinumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as natural rubber/latex found in the needle cover on the prefilled syringe), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: current/recent/returning infection (including hepatitis and tuberculosis), cancer. Ustekinumab can make you more likely to get infections or may worsen any current infections. Therefore, do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose. Avoid receiving BCG vaccines for one year after completing treatment with ustekinumab. Also avoid contact with people who have infections that may spread to others (such as chickenpox, flu). Wash your hands well to prevent the spread of infections. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. This drug may pass into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

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STELARA 130 MG/26 ML VIAL
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STELARA 45 MG/0.5 ML VIAL
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STELARA 45 MG/0.5 ML SYRINGE
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STELARA 90 MG/ML SYRINGE
STELARA 90 MG/ML SYRINGE
STELARA 90 MG/ML SYRINGE
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Faq for USTEKINUMAB - INJECTION

- Ustekinumab injection is used to treat certain inflammatory conditions such as psoriasis, psoriatic arthritis, and Crohn's disease.

- Ustekinumab works by targeting specific proteins in the body's immune system, blocking their action and reducing inflammation.

- The dosing schedule for Ustekinumab injection may vary depending on the condition being treated. In general, it is administered as an injection once every 12 weeks for the maintenance of psoriasis and psoriatic arthritis.

- Common side effects of Ustekinumab injection may include headache, tiredness, injection site reactions, upper respiratory tract infections, and nausea. However, it is important to note that individual experiences with side effects may vary.

- It is important to consult with your healthcare provider before using Ustekinumab injection if you are pregnant or breastfeeding. The potential risks and benefits should be carefully evaluated.

- Ustekinumab may interact with certain medications, so it is important to inform your healthcare provider about all the medicines you are taking, including prescription, over-the-counter, and herbal products.

- The response to Ustekinumab injection may vary from person to person. Some individuals may start experiencing improvements within a few weeks, while for others, it may take longer. It is important to follow the treatment plan provided by your healthcare provider.

- Ustekinumab can potentially increase the risk of serious infections. It is important to notify your healthcare provider if you develop any signs of infection, such as fever, cough, or persistent sore throat.

- Ustekinumab injection can be self-administered if you have received proper training from a healthcare professional. However, it is important to follow the specific instructions provided and consult your healthcare provider if you have any concerns or difficulties with self-administration.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.