TOFACITINIB EXTENDED-RELEASE - ORAL

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TOFACITINIB EXTENDED-RELEASE - ORAL

PHONETIC PRONUNCIATION: (TOE-fa-SYE-ti-nib)

COMMON BRAND NAME(S): Xeljanz XR

GENERIC NAME(S): tofacitinib citrate

Uses

USES: Tofacitinib is used to treat rheumatoid arthritis and psoriatic arthritis. It helps decrease pain, tenderness, and swelling in the joints.


How to use TOFACITINIB EXTENDED-RELEASE - ORAL

HOW TO USE: Read the Medication Guide provided by your pharmacist before you start taking tofacitinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Swallow the tablets whole. Do not crush, split, or chew the tablets. Doing so can release all of the drug at once, increasing the risk of side effects. The dosage is based on your medical condition, response to treatment, lab tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Tell your doctor if your condition does not get better or if it gets worse.

Side Effects

SIDE EFFECTS: See also Warning section. Headache or diarrhea may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly. An empty tablet shell may appear in your stool. This effect is harmless because your body has already absorbed the medication. People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk. Tell your doctor right away if you have any serious side effects, such as: unusual tiredness, fast heartbeat, shortness of breath, signs of liver disease (such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, such as: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking tofacitinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood/bone marrow problems (such as anemia), cancer, kidney disease, liver disease (such as hepatitis B or C), past/recent/current infections (such as tuberculosis, herpes zoster, HIV infection), stomach/intestinal/esophagus problems (such as ulcers, diverticulitis, narrowing, difficult/painful swallowing), lung disease. Tofacitinib can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details. Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be at greater risk for infections while using this drug. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Tell your doctor if you are planning pregnancy or become pregnant. It is unknown if this medication passes into breast milk. However, because of the possible risk to the infant, breast-feeding while using this drug and for at least 36 hours after the last dose is not recommended. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: See also Warning section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Other medications can affect the removal of tofacitinib from your body, which may affect how tofacitinib works. Examples include rifampin, among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

XELJANZ XR 11 MG TABLET
XELJANZ XR 11 MG TABLET
color
pink
shape
oblong
imprint
JKI 11
XELJANZ XR 11 MG TABLET
XELJANZ XR 11 MG TABLET
color
pink
shape
oblong
imprint
JKI 11

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Faq for TOFACITINIB EXTENDED-RELEASE - ORAL

Tofacitinib extended-release is an oral medication that belongs to a class of drugs known as Janus kinase (JAK) inhibitors. It is used to treat certain inflammatory conditions such as rheumatoid arthritis and ulcerative colitis.

Tofacitinib extended-release works by blocking certain enzymes called Janus kinases, which are involved in the inflammation process. By inhibiting these enzymes, it helps reduce inflammation and associated symptoms.

The common side effects of Tofacitinib extended-release may include headache, diarrhea, nausea, upper respiratory tract infections, and increased cholesterol levels. It is important to consult a healthcare professional for a complete list of potential side effects.

Tofacitinib extended-release is not approved for use in children. It is typically prescribed for adults with rheumatoid arthritis or ulcerative colitis.

Tofacitinib extended-release is usually taken once daily with or without food. It is important to follow the dosage instructions provided by a healthcare professional and not exceed the prescribed amount.

The use of Tofacitinib extended-release during pregnancy or while breastfeeding should be discussed with a healthcare professional. The potential risks and benefits need to be evaluated before making a decision.

Tofacitinib extended-release may interact with other medications. It is crucial to inform a healthcare professional about all the drugs you are currently taking, including prescription, over-the-counter, and herbal supplements, to avoid potential interactions.

The onset of action of Tofacitinib extended-release can vary depending on the individual and the condition being treated. It may take several weeks to experience the full benefits of the medication.

Tofacitinib extended-release can be used alone or in combination with other medications, depending on the specific condition being treated. It is important to follow the prescribed treatment plan provided by a healthcare professional.

Tofacitinib Extended-Release is an oral medication that belongs to a class of drugs known as Janus kinase (JAK) inhibitors. It is used to treat certain autoimmune diseases such as rheumatoid arthritis.

Tofacitinib Extended-Release works by inhibiting the activity of Janus kinases, which are enzymes involved in the signaling pathways of inflammatory and immune responses. By blocking these enzymes, it helps to reduce inflammation and alleviate symptoms associated with autoimmune diseases.

Tofacitinib Extended-Release is primarily used to treat adult patients with moderate to severe rheumatoid arthritis who have not responded adequately to other disease-modifying antirheumatic drugs (DMARDs).

Tofacitinib Extended-Release is taken orally, usually once daily with or without food. It is important to follow the prescribed dosage and instructions provided by the healthcare professional.

Common side effects of Tofacitinib Extended-Release include upper respiratory tract infections, headache, diarrhea, and nausea. Serious side effects may include infections, liver problems, and blood disorders. It is important to discuss any side effects with a healthcare professional.

Tofacitinib Extended-Release is not recommended for patients with severe liver problems or for those who have had or are at risk of serious infections. It is important to inform the healthcare professional about any medical conditions or medications being taken before starting Tofacitinib Extended-Release.

The effectiveness of Tofacitinib Extended-Release may vary among individuals. Some patients may experience improvement in symptoms within a few weeks, while others may take longer. It is important to follow the prescribed treatment plan and consult with a healthcare professional regarding the progress.

Tofacitinib Extended-Release may interact with certain medications. It is important to inform the healthcare professional about all the medications being taken, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions.

Tofacitinib Extended-Release should be used during pregnancy only if the potential benefits outweigh the risks. It is not recommended to breastfeed while taking this medication. It is important to discuss these concerns with a healthcare professional.

TOFACITINIB EXTENDED-RELEASE - ORAL Pricing Page Get Discount Coupon

Warning

WARNING: Tofacitinib may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. The most common serious infections include pneumonia, skin infections, shingles, a certain bowel disease (diverticulitis), swelling of the appendix (appendicitis), and urinary tract infections. The risk for infections may be higher if you also take other drugs that suppress the immune system (such as cyclosporine, tacrolimus). Tell your doctor right away if you have any signs of infection (such as a sore throat that doesn't go away, fever, chills, cough, trouble breathing, painful/frequent urination, non-healing skin sores). You should have a tuberculosis (TB) skin test before and during treatment with this medication. Tell your doctor if you have been near someone with tuberculosis or have lived or traveled in areas where certain fungal infections (such as coccidioidomycosis, histoplasmosis) are common. These areas include the Ohio and Mississippi River valleys and the southwestern United States. Though it is very unlikely to occur, there may be a risk of developing cancer (such as lymphoma, skin cancer) with this medication. Tell your doctor right away if you develop symptoms such as fever that doesn't go away, unusual lumps/growths, unexplained weight loss, night sweats, change in appearance or size of moles, or unusual skin changes. People with a kidney transplant who are also taking other drugs that suppress the immune system may be at greater risk for developing a certain white blood cell disorder (Epstein Barr Virus-associated post-transplant lymphoproliferative disorder) with this medication. Discuss the risks and benefits of treatment with your doctor.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.