TOBRAMYCIN/LOTEPREDNOL - OPHTHALMIC SUSPENSION

TOBRAMYCIN/LOTEPREDNOL - OPHTHALMIC SUSPENSION

PHONETIC PRONUNCIATION: (TOE-bra-MYE-sin/LOE-te-PRED-nol)

COMMON BRAND NAME(S): Zylet

GENERIC NAME(S): tobramycin/loteprednol etabonate

Uses

USES: This medication is used to treat conditions involving swelling (inflammation) of the eyes and to treat or prevent bacterial eye infections. This product contains tobramycin, an antibiotic that works by stopping the growth of bacteria. It also contains loteprednol, an anti-inflammatory corticosteroid that works by reducing swelling, redness, and itching. This medication treats/prevents only bacterial eye infections. It will not work for other types of eye infections and may worsen them (e.g., infections caused by viruses, fungi, mycobacteria). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.


How to use TOBRAMYCIN/LOTEPREDNOL - OPHTHALMIC SUSPENSION

HOW TO USE: This medication is applied to the eye(s) as directed by your doctor. To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface. Shake the bottle well before each dose. Do not wear contact lenses while you are using this medicine. Sterilize contact lenses according to manufacturer's directions, and check with your doctor before you begin using them again. Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place one drop into the pouch. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of your eye (near the nose) and apply gentle pressure. This will prevent the medication from draining out. Try not to blink and do not rub your eye. Repeat these steps if your dose is for more than 1 drop and for your other eye if so directed. Repeat as often as directed by your doctor. Your dosage is based on your medical condition and response to therapy. Do not rinse the dropper. Replace the dropper cap after each use. If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye. Do not use this medication more often than prescribed or for longer than 2 weeks unless directed by your doctor. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too soon may allow bacteria to continue to grow, which may result in a return of the infection. Inform your doctor if your condition does not improve in 2 days.

Side Effects

SIDE EFFECTS: Stinging/burning of the eyes for 1 to 2 minutes may occur when this medication is applied. Headache may also occur during treatment with this medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Use of this medication for prolonged/repeated periods may result in a new fungal eye infection and may increase your risk for other eye problems (e.g., glaucoma, cataracts, delayed wound healing). Do not use this medication for longer than prescribed. Tell your doctor right away if any of these unlikely but serious side effects occur: new or worsening eye symptoms (e.g., discharge, swelling, redness), vision problems, eye pain. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist if you are allergic to tobramycin or loteprednol; or to aminoglycoside antibiotics (e.g., gentamicin, neomycin); or to corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye problems (e.g., glaucoma). After you apply this drug, your vision may become temporarily unstable. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: aminoglycoside antibiotics (e.g., intravenous amikacin, gentamicin, tobramycin). This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Overdose

OVERDOSE: This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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ZYLET EYE DROPS

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ZYLET EYE DROPS

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Faq for TOBRAMYCIN/LOTEPREDNOL - OPHTHALMIC SUSPENSION

Tobramycin/Loteprednol ophthalmic suspension is a medication used to treat eye infections and reduce inflammation in the eyes.

Tobramycin is an antibiotic that kills or prevents the growth of bacteria causing infections in the eyes. Loteprednol is a corticosteroid that reduces inflammation and swelling in the eyes.

This medication is commonly used to treat bacterial eye infections, including conjunctivitis (pink eye), blepharitis, and keratitis. It is also effective in reducing inflammation associated with post-operative cataract surgery.

You should follow the instructions provided by your doctor or pharmacist. Typically, 1-2 drops are instilled into the affected eye(s) every 4-6 hours or as directed by your healthcare professional.

Some common side effects may include temporary stinging or burning sensation in the eyes, blurred vision, eye redness, or increased sensitivity to light. If you experience severe or persistent side effects, contact your doctor immediately.

It is generally recommended to avoid wearing contact lenses while using Tobramycin/Loteprednol ophthalmic suspension. Consult your eye care professional for guidance on when it is safe to resume wearing contact lenses.

If you miss a dose, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double dose to make up for a missed one.

Yes, Tobramycin/Loteprednol ophthalmic suspension can be used in children. However, the dosage and duration of treatment may vary based on the age and condition of the child. Consult a pediatrician for appropriate guidance.

The duration of treatment will depend on the type and severity of the eye infection or inflammation. Follow your doctor's instructions and complete the full course of treatment to ensure the infection is fully eradicated.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.