TIOPRONIN - ORAL

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TIOPRONIN - ORAL

PHONETIC PRONUNCIATION: (tie-oh-PRO-nin)

COMMON BRAND NAME(S): Thiola

GENERIC NAME(S): tiopronin

Uses

USES: This medication is used to prevent kidney stones in patients with a certain inherited disorder (cystinuria). Cystinuria occurs when there is too much of a certain natural substance (the amino acid cystine) in the urine, leading to formation of kidney stones. Tiopronin works by making cystine more dissolvable in the urine. This medication is usually used only after other methods are not successful in preventing kidney stones (e.g., drinking plenty of water, alkali therapy, special diet) or when patients cannot take the usual medication (d-penicillamine) for cystinuria.


How to use TIOPRONIN - ORAL

HOW TO USE: Take this medication by mouth 1 hour before or 2 hours after meals, usually 3 times daily or as directed by your doctor. Continue to drink plenty of water (e.g., 2 glasses of water with each meal, at bedtime, and during the night) and to take the alkali medication (e.g., potassium citrate) as directed by your doctor. Closely follow the diet recommended by your doctor. Dosage is based on your medical condition and response to therapy. In children, the dose is also based on weight. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Inform your doctor if your condition persists or worsens.

Side Effects

SIDE EFFECTS: Decreased sense of taste/smell, nausea, vomiting, loss of appetite, abdominal pain, or diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: signs of infection (e.g., fever, persistent sore throat), muscle/joint pain, swelling of lymph nodes, wrinkling/thinning skin, tiredness, fast/pounding heartbeat, easy bruising/bleeding, coughing up blood, signs of kidney problems (such as change in the amount of urine, painful urination, cloudy/bloody urine), dark urine, shortness of breath, muscle weakness, seizures, numbness/tingling of the arms/legs. Tell your doctor right away if any of these rare but very serious side effects occur: yellowing skin/eyes, persistent nausea/vomiting, severe abdominal/stomach pain. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking tiopronin, tell your doctor or pharmacist if you are allergic to this medication or have had very severe side effects (e.g., blood disorders) from it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood disorders (e.g., anemia, low platelet count), liver disease, kidney disease. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. This drug may pass into breast milk and could have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for TIOPRONIN - ORAL

- Tiopronin is an oral medication that belongs to a group of drugs called chelating agents. It helps to remove excess cystine from the body, which is a natural amino acid that can build up in the kidneys and cause kidney stones.

- Tiopronin is usually taken orally as a tablet or capsule, with or without food. The dosage and frequency will depend on the condition being treated and the individual response to the medication. It is important to follow the instructions provided by your doctor or pharmacist.

- Tiopronin is primarily used to prevent the formation of kidney stones in people with cystinuria, a genetic condition that causes high levels of cystine in the urine. It may also be used to treat other conditions as determined by your doctor.

- Common side effects of tiopronin may include stomach upset, nausea, diarrhea, loss of appetite, and a persistent, unpleasant odor to the urine. These side effects are usually temporary and may diminish over time. However, if they persist or worsen, it is important to inform your healthcare provider.

- Yes, there are some precautions and warnings associated with tiopronin. It may interact with certain medications, so it is crucial to inform your doctor about all the medications you are currently taking. Tiopronin may also cause an allergic reaction in some individuals, so it is essential to seek immediate medical attention if you experience any signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing. Additionally, it is important to stay well-hydrated while taking tiopronin to ensure proper kidney function.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.