THIOGUANINE - ORAL

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THIOGUANINE - ORAL

PHONETIC PRONUNCIATION: (THYE-oh-GWA-neen)

COMMON BRAND NAME(S): Tabloid

GENERIC NAME(S): thioguanine

Uses

USES: Thioguanine is used along with other drugs to treat a certain type of cancer (acute myeloid leukemia-AML). It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.


How to use THIOGUANINE - ORAL

HOW TO USE: Take this medication by mouth with or without food as directed by your doctor, usually once daily. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. Doing so may help decrease the risk of certain side effects (kidney problems). The dosage is based on your medical condition, weight, and response to treatment. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.

Side Effects

SIDE EFFECTS: Nausea, vomiting, loss of appetite, and mouth sores may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk. Tell your doctor right away if you have any serious side effects, including: joint pain/swelling, black stools, vomit that looks like coffee grounds, symptoms of liver disease (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine). This medication may decrease bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause easy bruising/bleeding. Tell your doctor right away if you develop any of the following symptoms: unusual tiredness, pale skin, signs of infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking thioguanine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain enzyme disorders (TPMT or NUDT15 deficiency). Thioguanine can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details. Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets. Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using thioguanine. Thioguanine may harm an unborn baby. Ask about reliable forms of birth control while using this medication. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication. It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

TABLOID 40 MG TABLET
TABLOID 40 MG TABLET
TABLOID 40 MG TABLET
color
white
shape
round
imprint
T40

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Faq for THIOGUANINE - ORAL

Thioguanine is a medication that belongs to the class of drugs known as antimetabolites. It is used to treat certain types of cancer, including acute lymphoblastic leukemia (ALL).

Thioguanine works by interfering with the growth and spread of cancer cells in the body. It inhibits the synthesis of DNA and RNA, which are essential for the replication and division of cancer cells.

Common side effects of Thioguanine may include nausea, vomiting, loss of appetite, diarrhea, stomach pain, hair loss, skin rash, and changes in the color of the skin or nails. It may also cause a decrease in the production of blood cells, leading to an increased risk of infection, bleeding, or anemia.

Thioguanine is usually taken orally as a tablet. The dosing schedule and duration of treatment may vary depending on the type and stage of cancer being treated. It is important to follow the instructions provided by your healthcare provider and not to adjust the dosage without consulting them.

Yes, Thioguanine should not be used by individuals who are allergic to it or have had severe bone marrow suppression caused by previous chemotherapy. It is also contraindicated in pregnant or breastfeeding women.

Thioguanine may interact with certain medications, including allopurinol (used to treat gout), warfarin (a blood thinner), and certain immunosuppressive drugs. It is important to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.

Thioguanine has been found to be effective in treating acute lymphoblastic leukemia (ALL) and is often used in combination with other chemotherapy drugs. However, the effectiveness of the drug may vary depending on individual factors such as the type and stage of cancer, as well as the patient's overall health.

Thioguanine may have long-term side effects, including an increased risk of developing secondary cancers, such as myelodysplastic syndrome or acute myeloid leukemia. Regular monitoring and follow-up with your healthcare provider are important to detect and manage any potential long-term effects.

If you miss a dose of Thioguanine, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.