TELMISARTAN/AMLODIPINE - ORAL

TELMISARTAN/AMLODIPINE - ORAL

PHONETIC PRONUNCIATION: (TEL-mi-SAR-tan/am-LOE-di-peen)

COMMON BRAND NAME(S): Twynsta

GENERIC NAME(S): telmisartan/amlodipine besylate

Uses

USES: This product is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains 2 medications: telmisartan and amlodipine. Telmisartan is an angiotensin receptor blocker (ARB) and amlodipine is a calcium channel blocker. They both work differently to relax the blood vessels so that blood can flow more easily. These medications are used together when one drug is not controlling your blood pressure. Your doctor may direct you to start taking the individual medications first, and then switch you to this combination product if it is the best dose combination for you.


How to use TELMISARTAN/AMLODIPINE - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking telmisartan/amlodipine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Do not remove the medication from the blister pack until right before using. The dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may take up to 4 weeks before you get the full benefit of this drug. Tell your doctor if your condition does not improve or if it worsens (such as your blood pressure readings remain high or increase).

Side Effects

SIDE EFFECTS: Dizziness or lightheadedness may occur as your body adjusts to the medication. Swelling hands/ankles/feet or flushing may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: fainting, fast/pounding/irregular heartbeat, signs of kidney problems (such as change in the amount of urine), symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat). Some people who already have severe heart disease may rarely develop worsening chest pain or a heart attack after starting this medication or increasing the dose. Get medical help right away if you experience: worsening chest pain, symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking this product, tell your doctor or pharmacist if you are allergic to either telmisartan or amlodipine; or to other calcium channel blockers (such as nifedipine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, high levels of potassium in the blood (hyperkalemia), loss of too much body water and/or minerals (dehydration), heart disease (such as aortic stenosis, heart failure), bile duct blockage. This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Too much sweating, diarrhea, or vomiting may cause you to feel lightheaded. Report prolonged diarrhea or vomiting to your doctor. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This product may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. Older adults may be more sensitive to the side effects of this drug, especially dizziness and change in the amount of urine (kidney problems). This medication is not recommended for use during pregnancy. It may harm an unborn baby. Consult your doctor for more details. (See also Warning section.) It is unknown if telmisartan passes into breast milk. Amlodipine passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: See also Precautions section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: aliskiren, lithium, ramipril, drugs that may increase the level of potassium in the blood (such as ACE inhibitors including benazepril/lisinopril, birth control pills containing drospirenone). Some products have ingredients that could raise your blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting, fast heartbeat.

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Faq for TELMISARTAN/AMLODIPINE - ORAL

Telmisartan/Amlodipine is an oral medication used to treat high blood pressure (hypertension). It is a combination of two drugs, Telmisartan (an angiotensin receptor blocker) and Amlodipine (a calcium channel blocker).

Telmisartan/Amlodipine works by relaxing blood vessels, allowing blood to flow more easily and reducing hypertension. Telmisartan blocks the action of a hormone called angiotensin II, which constricts blood vessels. Amlodipine relaxes blood vessels by blocking the entry of calcium into the smooth muscle cells of blood vessels.

The common side effects of this medication may include dizziness, headache, flushing, ankle swelling, nausea, and abdominal pain. However, it is important to note that not everyone experiences these side effects.

It is crucial to inform your healthcare provider about all the medications you are currently taking before starting Telmisartan/Amlodipine. Certain drugs, such as diuretics or other blood pressure medications, may interact with this combination medication and require dose adjustments or avoidance.

The time it takes for Telmisartan/Amlodipine to start working varies among individuals. However, some patients may notice a reduction in blood pressure within a few days of starting the medication. It is important to continue taking the medication as prescribed, even if you feel fine.

Telmisartan/Amlodipine is not recommended for use during pregnancy as it may harm the unborn baby. If you become pregnant or are planning to become pregnant, it is essential to consult your doctor to discuss alternative medications.

There are no specific dietary restrictions associated with Telmisartan/Amlodipine. However, it is generally recommended to follow a healthy diet that is low in salt, maintain a normal body weight, and limit alcohol consumption to help manage high blood pressure effectively.

Although rare, allergic reactions to Telmisartan/Amlodipine may occur. Symptoms of an allergic reaction may include rash, itching, swelling, severe dizziness, or difficulty breathing. If you experience any signs of an allergic reaction, seek medical attention immediately.

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.


Warning

WARNING: This drug can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. Therefore, it is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, tell your doctor right away.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.