TEDUGLUTIDE - INJECTION

TEDUGLUTIDE - INJECTION

PHONETIC PRONUNCIATION: (TE-due-GLOO-tide)

COMMON BRAND NAME(S): Gattex

GENERIC NAME(S): teduglutide

Uses

USES: Teduglutide is used by patients with Short Bowel Syndrome (SBS) who need intravenous (IV) nutrition and fluids. It may help to decrease the amount of intravenous nutrition needed by the patient. Teduglutide is similar to a natural hormone in your body (GLP-2). It works by helping to improve intestinal absorption of fluids and nutrients.


How to use TEDUGLUTIDE - INJECTION

HOW TO USE: Read the Medication Guide and the Instructions For Use Leaflet provided by your pharmacist before you start using teduglutide and each time you get a refill. Learn all preparation and usage instructions. If you have any questions, ask your doctor or pharmacist. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Do not shake the vial. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Inject this medication under the skin in the thigh, abdomen, or upper arm as directed by your doctor, usually once daily. The dosage is based on your medical condition, weight, and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

Side Effects

SIDE EFFECTS: Decreased appetite, trouble sleeping, cough, flu-like symptoms, or pain/redness/swelling at injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: nausea/vomiting that doesn't stop, swelling ankles/feet, unusual tiredness, sudden weight gain, severe constipation, stomach/abdominal pain or swelling, yellowing eyes/skin, dark urine, black/tarry stool, vomit that looks like coffee grounds. This medication may increase the risk of cancer. Your doctor will monitor you closely with lab and medical tests. See also Notes section. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using teduglutide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, cancer, gallbladder disease, disease of the pancreas (pancreatitis), intestinal or rectal polyps, heart problems (such as heart failure). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Interactions

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for TEDUGLUTIDE - INJECTION

Teduglutide injection is used for the treatment of intestinal failure associated with short bowel syndrome (SBS) in adults and children aged 1 year and older.

Teduglutide is a glucagon-like peptide-2 (GLP-2) analog that helps to improve the absorption of nutrients and fluids in the gut. It stimulates the regeneration and repair of the intestinal lining, reducing the dependence on parenteral nutrition in patients with short bowel syndrome.

Teduglutide is administered as a subcutaneous injection once daily. The injection is typically given in the thighs, arms, or abdomen.

Common side effects of teduglutide injection include abdominal pain, nausea, vomiting, upper respiratory tract infection, and injection site reactions.

The safety of teduglutide injection during pregnancy and breastfeeding has not been established. It is recommended to consult with a healthcare provider before using this medication in such cases.

The effects of teduglutide injection may vary from person to person. It may take several weeks to months of treatment before significant improvements in intestinal function are observed.

Yes, teduglutide injection is approved for use in children aged 1 year and older with intestinal failure associated with short bowel syndrome.

Your healthcare provider may provide you with specific dietary recommendations based on your individual needs. It is important to follow any dietary instructions provided and work closely with your healthcare team for optimal management of your condition.

Teduglutide injection is not a cure for short bowel syndrome but can help improve intestinal function and reduce the need for parenteral nutrition in patients with this condition.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.