SONIDEGIB - ORAL

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SONIDEGIB - ORAL

PHONETIC PRONUNCIATION: (SOE-ni-DEG-ib)

COMMON BRAND NAME(S): Odomzo

GENERIC NAME(S): sonidegib phosphate

Uses

USES: This medication is used to treat a certain type of skin cancer (basal cell carcinoma).


How to use SONIDEGIB - ORAL

HOW TO USE: Read the Medication Guide provided by your pharmacist before you start taking sonidegib and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily on an empty stomach, at least 1 hour before or 2 hours after a meal. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Tell your doctor if your condition does not get better or if it gets worse.

Side Effects

SIDE EFFECTS: Tiredness, abnormal taste, hair loss, headache, weight loss, nausea/vomiting, diarrhea, stomach/abdominal pain, mild itching, or decreased appetite may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: muscle pain/tenderness/weakness/spasms, signs of kidney problems (such as change in the amount of urine), missed periods. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking sonidegib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Do not donate blood while taking this drug and for 20 months after stopping treatment. This will prevent your blood being given to a pregnant woman. Older adults may be more sensitive to the side effects of this drug. This medication is not recommended for use during pregnancy. It may harm an unborn baby. Discuss the use of reliable forms of birth control (such as condoms, birth control pills) with your doctor. Consult your doctor for more details. (See also Warning section.) It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug and for 20 months after your last dose of this medication is not recommended. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Other medications can affect the removal of sonidegib from your body, which may affect how sonidegib works. Examples include azole antifungals (such as itraconazole, ketoconazole), efavirenz, modafinil, nefazodone, HIV protease inhibitors (such as ritonavir, saquinavir), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), telithromycin, among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

ODOMZO 200 MG CAPSULE
ODOMZO 200 MG CAPSULE
color
pink
shape
oblong
imprint
SONIDEGIB 200MG, NVR
ODOMZO 200 MG CAPSULE
ODOMZO 200 MG CAPSULE
color
pink
shape
oblong
imprint
SONIDEGIB 200MG, NVR

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Faq for SONIDEGIB - ORAL

Sonidegib is an oral medication used to treat patients with locally advanced basal cell carcinoma (BCC) that cannot be treated with surgery or radiation therapy.

Sonidegib works by inhibiting the Hedgehog signaling pathway, which is involved in the growth and development of basal cell carcinoma. By blocking this pathway, Sonidegib helps to inhibit the growth of cancer cells.

Sonidegib is taken orally as a capsule, usually once daily on an empty stomach, at least one hour before or two hours after a meal.

Common side effects of Sonidegib may include muscle spasms, hair loss, weight loss, fatigue, nausea, diarrhea, decreased appetite, taste changes, and vomiting.

Yes, there are some serious side effects associated with Sonidegib including severe muscle spasms, changes in heart rhythm, liver problems, and skeletal problems. It is important to inform the doctor about any concerning symptoms.

No, Sonidegib can cause harm to the developing fetus and is not recommended for use during pregnancy. Effective contraception is advised for both men and women during treatment with Sonidegib and for at least 20 months after the last dose.

Yes, Sonidegib may interact with other medications, including certain antibiotics, antiviral drugs, antifungal medications, antidepressants, and certain heart medications. It is important to inform the doctor about all the medications being taken.

The duration of Sonidegib treatment depends on various factors and should be determined by the treating doctor. It is important to follow the prescribed treatment plan and consult the doctor for any concerns.

Sonidegib can help to treat locally advanced basal cell carcinoma, but it may not cure the disease completely. The effectiveness of the treatment and the long-term outcome can vary for each individual.

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Warning

WARNING: Sonidegib is not recommended for use during pregnancy because it may cause serious harm (possibly death) to an unborn baby. Women of childbearing age must have a pregnancy test before starting this medication. They must also use reliable forms of birth control while taking sonidegib and for 20 months after the last dose of this medication. It is unknown if sonidegib passes into semen. Because of the possible risk of passing the drug on to a partner, men taking sonidegib (including men who have had a vasectomy) must use condoms during sex with women who are pregnant or of childbearing age, both during treatment with sonidegib and for 8 months after the last dose of this medication. Men should also not donate sperm during this time. If you or your partner become pregnant or think you may be pregnant, tell your doctor right away.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.