SODIUM PHENYLBUTYRATE POWDER - ORAL

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SODIUM PHENYLBUTYRATE POWDER - ORAL

PHONETIC PRONUNCIATION: (SO-dee-um fen-ill-BYOU-tih-rate)

COMMON BRAND NAME(S): Buphenyl

GENERIC NAME(S): sodium phenylbutyrate

Uses

USES: This medication is used along with diet changes for long-term treatment of a certain inherited disorder (urea cycle disorder). It helps remove a certain chemical (ammonia) from the body. Too much ammonia in the body can cause brain damage and sometimes death. This medication should not be used to treat sudden, severely high levels of ammonia in the body. Seek immediate medical attention if you have sudden symptoms of too much ammonia, such as trouble thinking, vomiting, irritability, slurred speech, trouble walking, fainting.


How to use SODIUM PHENYLBUTYRATE POWDER - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth or by feeding tube (nasogastric/gastric), exactly as directed by your doctor. Shake the bottle lightly before each use. Using the measuring device provided, measure out the dose prescribed by your doctor. Mix with solid or liquid food, and take all of the mixture right away. The dosage is based on your weight or body size, medical condition, and response to treatment. The total daily dose should be divided into equal amounts and taken with each meal or feeding (such as 3 to 6 times daily). Do not increase or decrease your dose without your doctor's approval. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Side Effects

SIDE EFFECTS: Loss of appetite or menstrual changes (delayed/irregular/absent periods) may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: drowsiness/lightheadedness, easy bruising/bleeding, fast/pounding heartbeat, mental/mood changes, signs of infection (such as fever, persistent sore throat), tiredness, signs of metabolic imbalance (such as rapid breathing, muscle twitching/spasms). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain heart problem (congestive heart failure), kidney disease, liver disease, swelling (edema). This medication contains salt (sodium). Before taking this medication, tell your doctor or pharmacist if you are on a low-salt diet. This drug may make you drowsy. Alcohol or marijuana can make you more drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication must not be used during pregnancy. It may harm an unborn baby. Discuss the use of reliable forms of birth control (such as condoms, birth control pills) with your doctor. If you become pregnant or think you may be pregnant, tell your doctor right away. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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BUPHENYL POWDER
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Faq for SODIUM PHENYLBUTYRATE POWDER - ORAL

Sodium Phenylbutyrate Powder - Oral is used to treat a genetic condition called urea cycle disorder (UCD). It helps the body get rid of excess ammonia to prevent it from building up to toxic levels.

Sodium Phenylbutyrate Powder - Oral works by increasing the excretion of waste nitrogen, including ammonia, through the urine. This helps to reduce the ammonia levels in the body, which is crucial for individuals with UCD.

Common side effects may include diarrhea, nausea, loss of appetite, vomiting, body odor, bad breath, headache, and fatigue. These side effects are usually mild and tend to improve over time.

Sodium Phenylbutyrate Powder - Oral is usually taken with food or a meal to reduce the likelihood of stomach upset. The dosage and frequency of administration will be determined by your healthcare provider based on your specific condition and medical history.

Yes, Sodium Phenylbutyrate Powder - Oral can be prescribed to children with UCD. However, the dosage will be adjusted based on the child's weight and age.

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

It is important to inform your healthcare provider about all the medications and supplements you are currently taking. Some medications, such as valproic acid, may interact with Sodium Phenylbutyrate Powder - Oral and affect its effectiveness.

It is essential to consult your healthcare provider if you are pregnant or planning to become pregnant before starting Sodium Phenylbutyrate Powder - Oral. The safety of this medication during pregnancy and breastfeeding has not been established, and the potential risks and benefits should be evaluated.

The effects of Sodium Phenylbutyrate Powder - Oral may vary between individuals. It may take a few weeks to months to notice significant improvements in the management of urea cycle disorder symptoms. Regular monitoring and follow-up with your healthcare provider are crucial to ensuring the medication's effectiveness.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.