SECUKINUMAB - INJECTION

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SECUKINUMAB - INJECTION

PHONETIC PRONUNCIATION: (SEK-ue-KIN-ue-mab)

COMMON BRAND NAME(S): Cosentyx

GENERIC NAME(S): secukinumab

Uses

USES: This medication is used to treat plaque psoriasis and certain types of arthritis (such as arthritis of the spine, psoriatic arthritis). Secukinumab belongs to a class of drugs known as monoclonal antibodies. It works by blocking a certain natural protein in your body (interleukin-17A) that may cause inflammation and swelling.


How to use SECUKINUMAB - INJECTION

HOW TO USE: Read the Medication Guide and the Instructions for Use leaflet provided by your pharmacist before you start using secukinumab and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Before treatment with this medication, your doctor will test you for tuberculosis (TB). Your doctor should also monitor you for symptoms of TB during and after treatment with this drug. If needed, treatment for tuberculosis or other infections should be given before receiving this medication. This medication is given by injection under your skin as directed by your doctor. The injection is given in the upper arms, thighs, or abdomen (at least 2 inches from your belly button). The dosage is based on your medical condition and response to treatment. Follow your doctor's instructions carefully. If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product instructions. Wash your hands before using this medication. Remove the medication from the refrigerator 15 to 30 minutes before you inject it to allow it to reach room temperature. Do not shake the medication. The medication should be clear or slightly yellow. Before using, check this product visually for cloudiness, particles, or discoloration. If you see any of these things, do not use the liquid. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject the drug into areas of the skin with scars or stretch marks or into skin that is irritated, sore, bruised, red, hardened, or affected by psoriasis. To lessen bruising, do not rub the injection site after a shot. Learn how to store and discard medical supplies safely. Do not reuse syringes. Use this medication regularly to get the most benefit from it. It may help to mark your calendar with a reminder. Tell your doctor if your condition does not improve or if it worsens.

Side Effects

SIDE EFFECTS: Diarrhea may occur. If this effect persists or worsens, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may lower your ability to fight infections. This may make you more likely to get a serious infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as fever, chills, persistent sore throat, white patches in the mouth, cough). Tell your doctor right away if you have any serious side effects, including: stomach/abdominal pain, diarrhea with blood/mucus. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using secukinumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as latex found in the needle cover on the prefilled syringe/pen), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: current/recent/returning infection (such as tuberculosis, herpes), bowel disease (such as Crohn's disease, ulcerative colitis). Secukinumab can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details. Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for SECUKINUMAB - INJECTION

Secukinumab is a medication that is injected to treat certain autoimmune diseases such as psoriasis, psoriatic arthritis, and ankylosing spondylitis. It works by blocking the action of a specific protein in the body called interleukin-17A, which is involved in inflammation.

Secukinumab is administered as an injection. It can be either self-injected or given by a healthcare professional.

The dosing schedule for Secukinumab varies depending on the specific condition being treated. For psoriasis, the recommended starting dose is usually one injection per week for the first five weeks, followed by one injection every four weeks. For psoriatic arthritis or ankylosing spondylitis, the initial dosing may be different and your doctor will provide specific instructions.

Like any medication, Secukinumab can cause side effects. Some common side effects include upper respiratory tract infections, injection site reactions, and headache. Serious side effects such as infections, allergic reactions, and inflammatory bowel disease have been reported but are rare. It is important to discuss the potential risks and side effects with your doctor before starting treatment.

It is recommended to avoid using Secukinumab during pregnancy unless the potential benefit outweighs the potential risks. The use of Secukinumab while breastfeeding is also not recommended. It is important to consult with your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this medication.

The onset of action can vary among individuals. Some patients may start to see improvement in their symptoms within a few weeks, while for others it may take longer. It is important to continue the treatment as prescribed and have regular follow-up visits with your doctor to assess the effectiveness.

There are no specific interactions between Secukinumab and alcohol. However, excessive alcohol consumption can have negative effects on overall health and may worsen certain conditions. It is recommended to drink alcohol in moderation, or as advised by your healthcare provider.

Before starting Secukinumab, it is generally recommended to complete all recommended vaccinations. While on this medication, live vaccines should be avoided. It is important to discuss any upcoming vaccinations with your doctor to ensure appropriate timing and safety.

Secukinumab should only be stopped under the guidance of your doctor. Abruptly stopping the medication can lead to a flare-up of symptoms. Your doctor will determine the appropriate duration of treatment based on your condition and response to therapy.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.