SACUBITRIL/VALSARTAN - ORAL

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SACUBITRIL/VALSARTAN - ORAL

PHONETIC PRONUNCIATION: (sak-UE-bi-tril/val-SAR-tan)

COMMON BRAND NAME(S): Entresto

GENERIC NAME(S): sacubitril/valsartan

Uses

USES: This product is used to treat certain types of heart failure. It may help you live longer and lower your chance of having to go to the hospital for heart failure. This product contains 2 medications: sacubitril and valsartan. Sacubitril belongs to a class of drugs called neprilysin inhibitors and valsartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). They work by relaxing blood vessels so that blood can flow more easily, which makes it easier for your heart to pump blood to your body.


How to use SACUBITRIL/VALSARTAN - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking this product and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this product by mouth with or without food as directed by your doctor, usually twice daily. The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this product at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. This product should not be taken with ACE inhibitors (such as captopril, enalapril) since your risk of serious side effects may increase. Do not take this product for at least 36 hours before or after taking an ACE inhibitor. Consult your doctor or pharmacist for more details. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Tell your doctor if you do not get better or if you get worse.

Side Effects

SIDE EFFECTS: Cough, dizziness, or lightheadedness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as change in the amount of urine), symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat), fainting. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking this product, tell your doctor or pharmacist if you are allergic to sacubitril; or to valsartan; or to other ARBs (such as candesartan, losartan); or to ACE inhibitors (such as quinapril, ramipril); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, loss of too much body water and minerals (dehydration), serious allergic reaction conditions that included swelling of your face/lips/tongue/throat/trouble breathing (such as angioedema, hereditary angioedema). This product may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. This product may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This product is not recommended for use during pregnancy. It may harm an unborn baby. Consult your doctor for more details. See also Warning section. It is unknown if this product passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: See also How to Use and Precautions sections. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this medication include: aliskiren, lithium, drugs that may increase the level of potassium in the blood (such as ACE inhibitors including benazepril/lisinopril, birth control pills containing drospirenone). Some products have ingredients that could worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting.

Images

ENTRESTO 49 MG-51 MG TABLET
ENTRESTO 49 MG-51 MG TABLET
ENTRESTO 49 MG-51 MG TABLET
color
pale yellow
shape
oblong
imprint
NVR, L1
ENTRESTO 49 MG-51 MG TABLET
ENTRESTO 49 MG-51 MG TABLET
ENTRESTO 49 MG-51 MG TABLET
color
pale yellow
shape
oblong
imprint
NVR, L1
ENTRESTO 49 MG-51 MG TABLET
ENTRESTO 49 MG-51 MG TABLET
ENTRESTO 49 MG-51 MG TABLET
color
pale yellow
shape
oblong
imprint
NVR, L1

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Faq for SACUBITRIL/VALSARTAN - ORAL

Sacubitril/valsartan is used to treat heart failure in patients who have a reduced ejection fraction.

Sacubitril/valsartan is a combination medication that works by relaxing blood vessels and reducing the strain on the heart. It also inhibits an enzyme responsible for breaking down a hormone that promotes vasodilation and natriuresis.

Common side effects may include low blood pressure, dizziness, cough, and increased blood potassium levels. It is important to consult your doctor if any side effects persist or worsen.

Sacubitril/valsartan may interact with certain medications, including other heart medications, potassium supplements, and non-steroidal anti-inflammatory drugs (NSAIDs). It is crucial to inform your doctor about all the medications you are taking to avoid potential interactions.

The usual dosage for sacubitril/valsartan is one tablet taken twice daily. It can be taken with or without food, but should be taken at the same time each day for consistent blood levels.

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Avoid taking a double dose to make up for a missed one.

Sacubitril/valsartan is not recommended during pregnancy as it may harm the unborn baby. It is important to discuss alternative options with your doctor if you are planning to become pregnant or are already pregnant.

Avoid using sacubitril/valsartan while breastfeeding, as it may pass into breast milk and harm the nursing infant. Discuss potential alternatives with your healthcare provider.

It may take a few weeks for sacubitril/valsartan to start working effectively. It is important to continue taking the medication as prescribed and consult your doctor if you don't notice any improvement in your condition.

SACUBITRIL/VALSARTAN - ORAL Pricing Page Get Discount Coupon

Warning

WARNING: Valsartan can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. It is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, tell your doctor right away.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.