ROLAPITANT - INJECTION

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ROLAPITANT - INJECTION

PHONETIC PRONUNCIATION: (roe-LA-pi-tant)

COMMON BRAND NAME(S): Varubi

GENERIC NAME(S): rolapitant HCl

Uses

USES: Rolapitant is used with other medications to help prevent delayed nausea and vomiting caused by cancer drug treatment (chemotherapy). It works by blocking one of the body's natural substances (substance P/neurokinin 1) that causes vomiting.


How to use ROLAPITANT - INJECTION

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist. This medication is given by injection into a vein as directed by your doctor, usually within 2 hours before you receive chemotherapy. The injection is usually given over 30 minutes. Do not use this medication more often than once every 2 weeks. Tell your doctor if you have nausea or vomiting.

Side Effects

SIDE EFFECTS: Stomach upset or mouth sores may occur. During the injection, side effects such as feelings of warmth, abdominal pain, dizziness, or numbness/tingling may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using rolapitant, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as soybean oil), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history. This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Rolapitant can slow down the removal of other medications from your body, which may affect how they work. This effect can last 4 weeks or longer after your dose of rolapitant. Examples of affected drugs include dextromethorphan, pimozide, thioridazine, among others. Other medications can affect the removal of rolapitant from your body, which may affect how rolapitant works. Examples include rifamycins (such as rifampin, rifabutin), among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for ROLAPITANT - INJECTION

ROLAPITANT - INJECTION is used to prevent nausea and vomiting caused by cancer chemotherapy.

ROLAPITANT - INJECTION is given as an injection by a healthcare professional. The dosage and schedule will be determined by your doctor.

Common side effects of ROLAPITANT - INJECTION may include diarrhea, constipation, fatigue, headache, and hiccups. If you experience any severe or persistent side effects, contact your doctor.

ROLAPITANT - INJECTION is usually given as a single dose before chemotherapy treatment. The effects of the medication can last for several days.

ROLAPITANT - INJECTION may cause drowsiness or dizziness. It is advisable to avoid activities that require mental alertness until you know how this medication affects you.

Tell your doctor about all the medications and supplements you are taking, as certain drugs may interact with ROLAPITANT - INJECTION. It is particularly important to inform your doctor if you are taking any medications that affect liver enzymes.

It is generally recommended to avoid alcohol while using ROLAPITANT - INJECTION, as it may increase the risk of certain side effects such as drowsiness or dizziness.

ROLAPITANT - INJECTION should be stored in a refrigerator between 2-8 degrees Celsius (36-46 degrees Fahrenheit). Do not freeze the medication.

If you miss a dose of ROLAPITANT - INJECTION, contact your healthcare provider for further instructions. It is important to follow your doctor's recommended schedule for optimal effectiveness.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.