RIBOCICLIB/LETROZOLE - ORAL
PHONETIC PRONUNCIATION: (RYE-boe-SYE-klib/LET-roe-zole)
COMMON BRAND NAME(S): Kisqali Femara Co-Pack
GENERIC NAME(S): ribociclib succinate/letrozole
Uses
USES: This product contains 2 medications: ribociclib tablets and letrozole tablets. These medications are used to treat breast cancer in women after menopause. Ribociclib works by slowing or stopping the growth of cancer cells. Letrozole works by decreasing the amount of estrogen the body makes, which helps slow down or reverse the growth of some breast cancers.
How to use RIBOCICLIB/LETROZOLE - ORAL
HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking ribociclib and letrozole tablets and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take ribociclib by mouth with or without food as directed by your doctor, usually once daily in the morning for 21 days, then stopping the medication for 7 days. Take letrozole by mouth with or without food as directed by your doctor, usually once daily in the morning for 28 days. This is one cycle of treatment. Continue taking these medications this way as directed by your doctor. Swallow the tablets whole. Do not crush, chew, or break the tablets. Also, do not take a tablet that is damaged or broken. If you vomit after taking a dose, do not take another dose on that day. Take your next dose at the regular time. The dosage is based on your medical condition, response to treatment, lab tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Use these medications regularly to get the most benefit from them. To help you remember, take them at the same time(s) each day. Do not increase your dose or use these drugs more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase. Avoid eating grapefruit or pomegranate, and avoid drinking grapefruit juice or pomegranate juice while taking these medications unless your doctor or pharmacist says you may do so safely. Grapefruit or pomegranate can increase the chance of side effects with ribociclib. Ask your doctor or pharmacist for more details. Since these drugs can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle these medications or breathe the dust from the tablets.
Side Effects
Precautions
Interactions
Overdose
Images
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- multi-color (2)
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- round
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- RIC or FV, NVR or CG
- color
- multi-color (2)
- shape
- round
- imprint
- RIC or FV, NVR or CG
- color
- multi-color (2)
- shape
- round
- imprint
- RIC or FV, NVR or CG
Reviews
Faq for RIBOCICLIB/LETROZOLE - ORAL
Ribociclib/Letrozole is a combination medication used for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in postmenopausal women.
Ribociclib is a cyclin-dependent kinase (CDK) inhibitor that works by blocking proteins called CDK4 and CDK6, which help cancer cells grow and divide. Letrozole is an aromatase inhibitor that reduces the production of estrogen, which fuels the growth of breast cancer cells. Together, they work to slow down or stop the growth of cancer cells.
The most common side effects of Ribociclib/Letrozole include fatigue, nausea, diarrhea, vomiting, constipation, headache, back pain, joint pain, low red blood cell count (anemia), low white blood cell count, low platelet count, and increased liver enzymes. Make sure to discuss any side effects with your healthcare provider.
Ribociclib/Letrozole is usually taken as a once-daily oral tablet, with or without food. It is important to follow your healthcare provider's instructions and take the medication at the same time each day. Do not crush, chew, or break the tablets. Swallow them whole with a glass of water.
Yes, there are several precautions and warnings associated with Ribociclib/Letrozole. It may cause severe or life-threatening liver problems, so regular monitoring of liver function is necessary. It may also cause a significant decrease in white blood cell count, increasing the risk of infections. Ribociclib/Letrozole should not be used during pregnancy as it may harm the unborn baby.
Yes, Ribociclib/Letrozole may interact with other medications, including certain antibiotics, antifungal medications, antidepressants, and heart medications. It is crucial to inform your doctor about all the medications you are taking, including prescription, over-the-counter, and herbal products, before starting Ribociclib/Letrozole.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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