PYRAZINAMIDE - ORAL

PYRAZINAMIDE - ORAL

PHONETIC PRONUNCIATION: (pir-uh-ZIN-uh-mide)

GENERIC NAME(S): pyrazinamide

Uses

USES: Pyrazinamide is used with other medications to treat tuberculosis (TB). It is an antibiotic and works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.


How to use PYRAZINAMIDE - ORAL

HOW TO USE: Take this medication by mouth with or without food, usually once daily or twice weekly, or as directed by your doctor. Dosage is based on your age, weight, medical condition, and response to treatment. For the best effect, take this antibiotic at evenly spaced times. If you are taking this medication daily, take it at the same time each day. If you are taking this medication on a weekly schedule, take it on the same days of the week and at the same time each day. Mark the days on the calendar when you need to take the medication. Continue to take this medication (and other TB medications) until the full prescribed amount is finished, even if symptoms disappear. Stopping the medication too early or skipping doses may allow the bacteria to continue to grow, which may result in a return of the infection and cause the infection to be more difficult to treat (resistant). Tell your doctor if your condition persists or worsens.

Side Effects

SIDE EFFECTS: Nausea, vomiting, loss of appetite, or mild muscle/joint pain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: symptoms of liver disease (such as persistent nausea/vomiting, unusual tiredness/weakness, severe stomach/abdominal pain, yellowing eyes/skin, dark urine), painful/swollen joints. Tell your doctor right away if any of these rare but serious side effects occur: signs of kidney problems (such as change in the amount of urine), easy bleeding/bruising, fast heartbeat. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever that doesn't go away, new or worsening lymph node swelling, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking pyrazinamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, diabetes, gout, high uric acid level in the blood, alcohol use. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Alcohol may increase the risk of liver disease. Avoid alcoholic beverages while using this medication. Pyrazinamide may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. This medication passes into breast milk but the effect on a nursing infant is unknown. Discuss the risks and benefits with your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring. To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval. This medication may interfere with certain laboratory tests (including urine ketone tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. This document does not contain all possible interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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PYRAZINAMIDE 500 MG TABLET

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PYRAZINAMIDE 500 MG TABLET

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PYRAZINAMIDE 500 MG TABLET

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VP 012
PYRAZINAMIDE 500 MG TABLET

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VP 012
PYRAZINAMIDE 500 MG TABLET

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Faq for PYRAZINAMIDE - ORAL

Pyrazinamide is an oral medication that is used as part of a combination therapy to treat tuberculosis (TB) infection.

Pyrazinamide works by killing the bacteria that cause tuberculosis. It is believed to disrupt the enzymes needed for the bacteria's survival.

Pyrazinamide is usually taken once a day with food. It is important to follow the instructions provided by your healthcare provider or pharmacist.

Common side effects of Pyrazinamide include nausea, vomiting, loss of appetite, joint pain, and rash. It is important to report any side effects to your healthcare provider.

Pyrazinamide is generally considered safe to use during pregnancy, but it is important to discuss the risks and benefits with your healthcare provider.

Pyrazinamide may interact with other medications such as rifampin or antacids. It is important to inform your healthcare provider about all the medications you are taking.

The duration of Pyrazinamide treatment depends on the specific TB infection and the overall treatment plan determined by your healthcare provider. It is important to complete the full course of treatment as prescribed.

Pyrazinamide can be used in children, but the dosage and duration of treatment may be different. Your healthcare provider will determine the appropriate dosage for your child.

If you miss a dose of Pyrazinamide, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double dose.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.