PREGABALIN - ORAL

PREGABALIN - ORAL

PHONETIC PRONUNCIATION: (pree-GAH-ba-lin)

COMMON BRAND NAME(S): Lyrica

GENERIC NAME(S): pregabalin

Uses

USES: This medication is used to treat pain caused by nerve damage due to diabetes, shingles (herpes zoster) infection, or spinal cord injury. This medication is also used to treat pain in people with fibromyalgia. It is also used with other medications to treat certain types of seizures (focal seizures).


How to use PREGABALIN - ORAL

HOW TO USE: Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using pregabalin and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually 2 to 3 times a day with or without food. The dosage is based on your medical condition, kidney function, and response to treatment. Children's dosage is also based on weight. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. To reduce your risk of side effects (such as dizziness and drowsiness), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. This drug works best when the amount of medicine in your body is kept at a constant level. Therefore it is best to take pregabalin at evenly spaced intervals throughout the day and night. Do not stop taking this medication without consulting your doctor. Some conditions (such as seizures) may become worse when this drug is suddenly stopped. Also, you may experience symptoms such as difficulty sleeping, nausea, headache and diarrhea. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Report any new or worsening symptoms right away. Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details. Tell your doctor if your condition persists or worsens.

Side Effects

SIDE EFFECTS: Drowsiness, dizziness, dry mouth, constipation, difficulty concentrating, or weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any unlikely but serious side effects, including: blurred vision, unusual bleeding/bruising, unsteadiness, confusion, muscle pain/tenderness/weakness (especially if you are tired or have a fever), swelling of hands/legs/feet, signs of kidney problems (such as change in the amount of urine). A small number of people who take anticonvulsants for any condition (such as seizure, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor right away if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking pregabalin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart failure), kidney disease, history of an allergic reaction which included itching/swelling of the face/lips/tongue/throat (angioedema), personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol). This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of this drug, especially drowsiness, dizziness, unsteadiness, and confusion. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. This drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. A product that may interact with this drug is: orlistat. Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for PREGABALIN - ORAL

Pregabalin is an oral medication that belongs to the class of drugs known as anticonvulsants. It works by reducing the abnormal electrical activity in the brain, thus effectively treating seizures, nerve pain, and certain psychiatric disorders.

Pregabalin is frequently prescribed for the treatment of nerve pain caused by conditions such as diabetic neuropathy, postherpetic neuralgia (nerve pain following shingles), fibromyalgia, and spinal cord injury. It is also used as an adjunctive therapy for partial onset seizures in adults and for the treatment of generalized anxiety disorder.

Pregabalin works by binding to certain calcium channels in the brain and spinal cord, which reduces the release of neurotransmitters involved in pain signaling. This helps to dampen the excessive nerve activity responsible for the sensation of pain.

The most commonly reported side effects of pregabalin include dizziness, drowsiness, dry mouth, blurred vision, weight gain, and swelling in the hands, legs, or feet. It may also cause difficulty concentrating, confusion, and mood changes. However, not everyone experiences these side effects, and many are mild and temporary.

The onset of pregabalin's effects can vary from person to person and also depends on the specific condition being treated. Generally, it may take a few days to a couple of weeks to experience significant pain relief.

While pregabalin is not classified as a controlled substance or considered highly addictive, it can still cause dependence. Abruptly stopping the medication may result in withdrawal symptoms such as anxiety, insomnia, nausea, sweating, and diarrhea. It is always important to follow your doctor's instructions while taking pregabalin.

Pregabalin may interact with some medications, including opioids, benzodiazepines, and alcohol, leading to increased side effects such as excessive drowsiness or respiratory depression. Therefore, it's essential to inform your doctor about all the medications and supplements you are currently taking.

Pregabalin should be used during pregnancy only if the potential benefits outweigh the potential risks. It is known to pass into breast milk, so breastfeeding mothers should discuss the risks and benefits with their healthcare provider before taking pregabalin.

Yes, healthcare providers may prescribe pregabalin for off-label uses, meaning for conditions not specifically approved by the FDA. Some examples include the treatment of social anxiety disorder, insomnia, and alcohol withdrawal symptoms. However, it's important to discuss these off-label uses with your doctor and understand the potential risks and benefits.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.