PERAMPANEL - ORAL

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PERAMPANEL - ORAL

PHONETIC PRONUNCIATION: (per-AM-pa-nel)

COMMON BRAND NAME(S): Fycompa

GENERIC NAME(S): perampanel

Uses

USES: Perampanel is used to treat certain types of seizures (including focal and generalized tonic-clonic seizures). Perampanel belongs to a class of drugs known as anticonvulsants.


How to use PERAMPANEL - ORAL

HOW TO USE: Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking perampanel and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily at bedtime. If you are using the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased. Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details. Tell your doctor if your condition does not improve or if it worsens.

Side Effects

SIDE EFFECTS: See also Warning Section. Dizziness, a feeling of spinning, unsteadiness, trouble walking, loss of balance, drowsiness, weakness, nausea, vomiting, headache, or weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: blurred/double vision, frequent falls. A small number of people who take anticonvulsants for any condition (such as seizures, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor right away if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking perampanel, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, kidney problems, mental/mood disorders, personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol), galactose intolerance (such as Lapp lactase deficiency or glucose-galactose malabsorption). This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of this drug, especially falls, drowsiness, and weakness. During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. However, since untreated seizures are a serious condition that can harm both a pregnant woman and her unborn baby, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. A product that may interact with this drug is: orlistat. Other medications can affect the removal of perampanel from your body, which may affect how perampanel works. Examples include rifamycins (such as rifabutin), St. John's wort, among others. This medication may decrease the effectiveness of levonorgestrel-containing birth control. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use reliable non-hormonal backup birth control methods (such as condoms, diaphragm with spermicide) while using perampanel and for a month after you stop using perampanel. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: mental/mood/behavior changes such as agitation, aggressive behavior.

Images

FYCOMPA 2 MG TABLET
FYCOMPA 2 MG TABLET
FYCOMPA 2 MG TABLET
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FYCOMPA 4 MG TABLET
FYCOMPA 4 MG TABLET
FYCOMPA 4 MG TABLET
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FYCOMPA 6 MG TABLET
FYCOMPA 6 MG TABLET
FYCOMPA 6 MG TABLET
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FYCOMPA 8 MG TABLET
FYCOMPA 8 MG TABLET
FYCOMPA 8 MG TABLET
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FYCOMPA 10 MG TABLET
FYCOMPA 10 MG TABLET
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FYCOMPA 12 MG TABLET
FYCOMPA 12 MG TABLET
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FYCOMPA 0.5 MG/ML ORAL SUSP
FYCOMPA 0.5 MG/ML ORAL SUSP
FYCOMPA 0.5 MG/ML ORAL SUSP
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Faq for PERAMPANEL - ORAL

Perampanel is an oral medication primarily used to treat epilepsy in patients aged 4 years and older who are experiencing partial-onset seizures or generalized tonic-clonic seizures.

Perampanel works by blocking certain receptors in the brain called AMPA receptors. By doing so, it helps reduce the excessive electrical activity in the brain that causes seizures.

The recommended starting dosage of Perampanel is generally 2 mg per day, which can be increased gradually based on the individual patient's response and tolerability. The maximum recommended dosage is 12 mg per day.

Some common side effects of Perampanel include dizziness, sleepiness, tiredness, irritability, mood changes, balance problems, coordination difficulties, and falls. It may also cause behavioral or psychiatric changes, including aggression, agitation, and suicidal thoughts.

Yes, Perampanel can be used in children aged 4 years and older for the treatment of epilepsy. However, its use should be carefully monitored by a pediatric neurologist.

Perampanel can be taken with certain other epilepsy medications, but it may also interact with others. It is important to consult with a healthcare professional to determine the best medication combination and dosage for each individual patient.

The effectiveness of Perampanel may vary from person to person. Some individuals may experience a reduction in seizures within a few weeks, while others may take longer. It is important to continue taking the medication as prescribed by a doctor for a sufficient period to assess its effectiveness.

The use of Perampanel during pregnancy is generally not recommended unless the potential benefits outweigh the potential risks to the fetus. It is essential to discuss any plans for pregnancy or potential risks with a healthcare professional before taking Perampanel.

Consuming alcohol while taking Perampanel increases the risk of side effects such as dizziness, drowsiness, and impaired coordination. It is advisable to avoid or limit alcohol consumption while on this medication.

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Warning

WARNING: Perampanel may cause or worsen mental/mood disorders. Tell your doctor right away if you or your family/caregiver notice any unusual behavior changes (including aggression, attempts to hurt others, impulsive actions) or other mental/mood changes (including anxiety, irritability, hostile/angry feelings, paranoia, hallucinations, delusions, thoughts of harming others). Be especially watchful for these symptoms when you first start this medication or when the dose is changed. These symptoms may also occur even after stopping perampanel. Do not drink alcoholic beverages while taking perampanel because alcohol may make these symptoms worse.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.