PENTAZOCINE/NALOXONE - ORAL

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PENTAZOCINE/NALOXONE - ORAL

PHONETIC PRONUNCIATION: (pen-TAZZ-oh-seen/nal-OX-own)

COMMON BRAND NAME(S): Talwin NX

GENERIC NAME(S): pentazocine HCl/naloxone HCl

Uses

USES: This product is used to treat moderate to severe pain. It contains 2 medications, pentazocine and naloxone. Pentazocine is an opioid (narcotic) pain reliever. It acts on certain centers in the brain to give you pain relief. Naloxone helps to prevent misuse of this product. It blocks the effect of pentazocine and may cause withdrawal reactions if this product is dissolved and injected. Naloxone does not have any effect when taken by mouth.


How to use PENTAZOCINE/NALOXONE - ORAL

HOW TO USE: Take this medication by mouth with or without food, usually every 3 to 4 hours or as directed by your doctor. If you have nausea, it may help to take this drug with food. Consult your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible). The dosage is based on your medical condition and response to treatment. Do not take more than 600 milligrams of pentazocine in a 24-hour period. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed. Pain medications work best if they are used when the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well. If you have been regularly using other opioid pain medications (for example, morphine, methadone), withdrawal reactions (such as restlessness, watery eyes, widened pupils, sweating, runny nose) may occur when you start this product. Consult with your doctor or pharmacist for more details. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as restlessness, watery eyes, widened pupils, sweating, runny nose) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away. When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well. Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details. Tell your doctor if your pain persists or worsens.

Side Effects

SIDE EFFECTS: See also Warning section. Nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, increased sweating, headache, or dry mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To prevent constipation, eat a diet adequate in fiber, drink plenty of water, and exercise. Consult your pharmacist for help in selecting a laxative (such as a stimulant type with stool softener). To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as agitation, hallucinations, confusion), difficulty urinating, vision changes, fast heartbeat, stomach/abdominal pain, signs of infection (such as sore throat that doesn't go away, fever), signs of your adrenal glands not working well (such as loss of appetite, unusual tiredness, weight loss). Get medical help right away if you have any very serious side effects, including: slow/shallow breathing, seizures, fainting, severe drowsiness/difficulty waking up. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking this product, tell your doctor or pharmacist if you are allergic to pentazocine or naloxone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (such as seizures, head injury, tumor), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), gallbladder disease, heart problems (such as irregular heartbeat, recent heart attack), kidney disease, liver disease, mental/mood disorders (such as confusion, depression, thoughts of suicide), personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol), stomach/intestinal problems (such as blockage, constipation, diarrhea due to infection, paralytic ileus), disease of the pancreas (pancreatitis), difficulty urinating (such as due to enlarged prostate), certain blood disorder (porphyria). This drug may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist that you are using this medication. Older adults may be more sensitive to the side effects of this drug, especially confusion, dizziness, drowsiness, and slow/shallow breathing. During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Discuss the risks and benefits with your doctor. (See also Warning section.) This drug may pass into breast milk and may have undesirable effects on a nursing infant. Tell the doctor right away if your baby develops unusual sleepiness, difficulty feeding, or trouble breathing. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: See also Warning and How to Use sections. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: fluoxetine, naltrexone. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication. The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is taken with other products that may also cause drowsiness or breathing problems. Tell your doctor or pharmacist if you are taking other products such as other opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking. This medication may interfere with certain laboratory tests (including amylase/lipase levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, give them naloxone by itself if available, then call 911. If the person is awake and has no symptoms, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: slow/shallow breathing, severe drowsiness, severe dizziness, pinpoint pupils, coma.

Images

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PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
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WATSON, 395 50 0.5
PENTAZOCINE-NALOXONE TABLET
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PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
color
light yellow
shape
oblong
imprint
NL 680
PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
color
light green
shape
oblong
imprint
WATSON, 395 50 0.5
PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
color
light green
shape
oblong
imprint
WATSON, 395 50 0.5
PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
PENTAZOCINE-NALOXONE TABLET
color
light green
shape
oblong
imprint
WATSON, 395 50 0.5

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Faq for PENTAZOCINE/NALOXONE - ORAL

Pentazocine/Naloxone is a medication that combines two drugs: pentazocine, which is an opioid pain reliever, and naloxone, which is an opioid receptor antagonist used to reverse the effects of opioids.

Pentazocine works by binding to certain opioid receptors in the brain and spinal cord, blocking pain sensations. Naloxone, on the other hand, binds to opioid receptors and reverses or blocks the effects of other opioids in the body.

Pentazocine/Naloxone is used to relieve moderate to severe pain. It is also used to treat opioid dependence by reducing the effects of other opioids and helping to prevent withdrawal symptoms.

Common side effects of Pentazocine/Naloxone may include dizziness, drowsiness, headache, nausea, vomiting, constipation, dry mouth, sweating, or itching.

Pentazocine/Naloxone can be habit-forming if used for an extended period or in higher doses than prescribed. It is important to take the medication exactly as prescribed by the healthcare provider.

Since naloxone is included in the medication, it can precipitate withdrawal symptoms in individuals who are physically dependent on opioids. It is important not to abruptly stop taking Pentazocine/Naloxone without consulting a healthcare professional.

Inform your doctor about any known allergies, medical conditions, or medications you are currently taking. It is crucial to disclose any history of drug addiction or if you have used opioids within the past 7-10 days.

It is recommended to consult a doctor before using Pentazocine/Naloxone during pregnancy or while breastfeeding. The potential risks and benefits should be weighed carefully.

Drinking alcohol while taking Pentazocine/Naloxone may increase the risk of side effects such as dizziness or drowsiness. It is best to avoid alcohol while on this medication.

PENTAZOCINE/NALOXONE - ORAL Pricing Page Get Discount Coupon

Warning

WARNING: Pentazocine has a risk for abuse and addiction, which can lead to overdose and death. Pentazocine may also cause severe, possibly fatal, breathing problems. To lower your risk, your doctor should have you take the smallest dose of pentazocine that works, and take it for the shortest possible time. See also How to Use section for more information about addiction. The risk for severe breathing problems is higher when you start this medication and after a dose increase, or if you take the wrong dose/strength. Taking this medication with alcohol or other drugs that can cause drowsiness or breathing problems may cause very serious side effects, including death. Be sure you know how to take this medication and what other drugs you should avoid taking with it. See also Drug Interactions section. Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/dizziness, difficulty waking up. This medication should only be taken by mouth. Do not try to dissolve and inject the tablets. Injecting this product, alone or with other substances, may cause serious, possibly fatal, side effects. Keep this medicine in a safe place to prevent theft, misuse, or abuse. If someone accidentally swallows this drug, get medical help right away. Before using this medication, women of childbearing age should talk with their doctor(s) about the risks and benefits. Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It may slightly increase the risk of birth defects if used during the first two months of pregnancy. Also, using it for a long time or in high doses near the expected delivery date may harm the unborn baby. To lessen the risk, take the smallest effective dose for the shortest possible time. Babies born to mothers who use this drug for a long time may develop severe (possibly fatal) withdrawal symptoms. Tell the doctor right away if you notice any symptoms in your newborn baby such as crying that doesn't stop, slow/shallow breathing, irritability, shaking, vomiting, diarrhea, poor feeding, or difficulty gaining weight.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.