OXYCODONE/ACETAMINOPHEN EXTENDED-RELEASE - ORAL
PHONETIC PRONUNCIATION: (OX-i-KOE-done/a-SEET-a-MIN-oh-fen)
COMMON BRAND NAME(S): Xartemis XR
GENERIC NAME(S): oxycodone HCl/acetaminophen
Uses
USES: This combination medication is used to help relieve severe pain. It contains a opioid (narcotic) pain reliever (oxycodone) and a non-opioid pain reliever (acetaminophen). Oxycodone works in the brain to change how your body feels and responds to pain. Acetaminophen gives added pain relief and can also reduce a fever.
How to use OXYCODONE/ACETAMINOPHEN EXTENDED-RELEASE - ORAL
HOW TO USE: See also Warning section. Read the Medication Guide provided by your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Do not change brands of this medication unless specifically directed by your doctor. If you take a different brand, you may need to take a different amount or take it on a different schedule. Take this medication by mouth as directed by your doctor, usually twice a day (12 hours apart). Do not pre-soak, lick, or otherwise wet the tablet before placing it in your mouth, since the tablet may swell and become sticky when wet. If your dose is for more than one tablet, you should take one tablet at a time. Take each tablet with enough water to make sure you completely swallow it right after placing it in your mouth. This tablet should not be given through a tube in the throat, stomach, or gut, since it may swell and block the tube. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible). The dosage is based on your medical condition and response to treatment. Do not increase your dose, or take it more often or for a longer time than prescribed. Properly stop the medication when so directed. After you stop taking this medication, flush any unused tablets down the toilet. Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well. Before you start taking this medication, ask your doctor or pharmacist if you should stop or change how you use your other opioid medication(s). Other pain relievers (such as ibuprofen, naproxen) may also be prescribed. Ask your doctor or pharmacist about using oxycodone safely with other drugs. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as restlessness, watering eyes, runny nose, nausea, sweating, muscle aches) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Ask your doctor or pharmacist for more details, and report any withdrawal reactions right away. When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well. Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details. Tell your doctor if your pain persists or worsens.
Side Effects
Precautions
Interactions
Overdose
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Faq for OXYCODONE/ACETAMINOPHEN EXTENDED-RELEASE - ORAL
Oxycodone/Acetaminophen Extended-Release is prescribed to relieve moderate to severe pain.
This medication works by binding to opioid receptors in the brain, spinal cord, and other areas of the body, reducing the sensation of pain.
Common side effects may include nausea, constipation, vomiting, drowsiness, dizziness, and lightheadedness.
The dosage and frequency of taking this medication will depend on the severity of your pain and your doctor's instructions. It is important to follow the prescribed dosing schedule.
Yes, this medication has a high potential for addiction and abuse. It should only be used as prescribed and under the supervision of a healthcare professional.
It is not recommended to consume alcohol while taking this medication as it can increase the risk of serious side effects such as drowsiness, dizziness, and difficulty breathing.
Oxycodone can be detected in urine for 1-3 days, while it may be detected in saliva for up to 4 days. The exact duration can vary based on factors such as metabolism and individual differences.
It is not advisable to drive or operate heavy machinery while under the influence of this medication, as it can cause drowsiness and impair your ability to safely perform these activities.
Several medications, including certain antidepressants, antifungal drugs, and tranquilizers, may interact with this medication. It is essential to inform your doctor about all the medications you are taking to avoid potential interactions.
Warning
WARNING: Oxycodone/acetaminophen has a risk for abuse and addiction, which can lead to overdose and death. Oxycodone/acetaminophen may also cause severe, possibly fatal, breathing problems. To lower your risk, your doctor should have you take the smallest dose of oxycodone/acetaminophen that works, and take it for the shortest possible time. See also How to Use section for more information about addiction. The risk for severe breathing problems is higher when you start this medication and after a dose increase, or if you take the wrong dose/strength. Taking this medication with alcohol or other drugs that can cause drowsiness or breathing problems may cause very serious side effects, including death. Also, other medications can affect the removal of oxycodone/acetaminophen from your body, which may affect how oxycodone/acetaminophen works. Be sure you know how to take oxycodone/acetaminophen and what other drugs you should avoid taking with it. See also Drug Interactions section. Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/dizziness, difficulty waking up. Keep this medicine in a safe place to prevent theft, misuse, or abuse. If someone accidentally swallows this drug, get medical help right away. One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. People with liver problems and children should take less acetaminophen. Ask your doctor or pharmacist how much acetaminophen is safe to take. Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first. Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough-and-cold products). Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. Get medical help right away if you take too much acetaminophen (overdose), even if you feel well. Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, yellowing eyes/skin, and dark urine. Daily alcohol use, especially when combined with acetaminophen, may damage your liver. Avoid alcohol. Before using this medication, women of childbearing age should talk with their doctor(s) about the risks and benefits. Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It may slightly increase the risk of birth defects if used during the first two months of pregnancy. Also, using it for a long time or in high doses near the expected delivery date may harm the unborn baby. To lessen the risk, take the smallest effective dose for the shortest possible time. Babies born to mothers who use this drug for a long time may develop severe (possibly fatal) withdrawal symptoms. Tell the doctor right away if you notice any symptoms in your newborn baby such as crying that doesn't stop, slow/shallow breathing, irritability, shaking, vomiting, diarrhea, poor feeding, or difficulty gaining weight.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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