NIFEDIPINE SUSTAINED-RELEASE - ORAL

NIFEDIPINE SUSTAINED-RELEASE - ORAL

PHONETIC PRONUNCIATION: (nye-FED-i-peen)

COMMON BRAND NAME(S): Procardia XL

GENERIC NAME(S): nifedipine

Uses

USES: Nifedipine is used alone or in combination with other drugs to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is also used for certain types of chest pain (angina). It may help increase your ability to exercise and decrease the frequency of chest pain attacks. It should not be used to treat chest pain when it occurs. Use other medications (e.g., sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor. Consult your doctor or pharmacist for more details. This medication is known as a calcium channel blocker. It works by relaxing and widening blood vessels so blood can flow more easily.


How to use NIFEDIPINE SUSTAINED-RELEASE - ORAL

HOW TO USE: Take this medication by mouth, with or without food, usually once daily or as directed by your doctor. Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Your doctor may gradually increase your dose. Follow your doctor's instructions carefully. Dosage is based on your medical condition and response to treatment. Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit juice can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details. Use this medication regularly in order to get the most benefit from it. Remember to take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Do not suddenly stop taking this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. Tell your doctor if your condition worsens (e.g., increase in your routine blood pressure readings).

Side Effects

SIDE EFFECTS: Headache, dizziness, nausea, flushing, constipation, leg/muscle cramps, or sexual problems may occur. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. An empty tablet shell may appear in your stool. This is harmless since your body has already absorbed the medication. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: swelling of the ankles/feet, shortness of breath, unusual weakness/tiredness. Tell your doctor right away if any of these rare but very serious side effects occur: fast/slow/irregular heartbeat, fainting, mental/mood changes, swollen/tender gums, vision changes, severe constipation, severe stomach/abdominal pain, black stools. Although this medication is effective in preventing chest pain (angina), some people who already have severe heart disease may rarely develop worsening chest pain or a heart attack after starting this medication or increasing the dose. Get medical help right away if you experience: worsening chest pain, symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating). A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers (e.g., amlodipine, felodipine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart diseases (e.g., congestive heart failure, aortic stenosis), liver problems, esophagus/stomach/intestine problems (e.g., narrowing/stricture, motility disorders, obstruction), kidney problems, a certain metabolic disorder (porphyria). Before having surgery, tell your doctor or dentist that you are taking this medication. This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Nifedipine passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: alpha blockers (such as doxazosin), calcium or magnesium sulfate received through a vein, digoxin, fentanyl, melatonin. Other medications can affect the removal of nifedipine from your body, which may affect how nifedipine works. Examples include apalutamide, cimetidine, enzalutamide, quinupristin/dalfopristin, St. John's wort, rifamycins (such as rifabutin, rifampin), drugs used to treat seizures (such as carbamazepine, phenytoin), among others. Some products have ingredients that could raise your heart rate or blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting, fast/slow/irregular heartbeat.

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Faq for NIFEDIPINE SUSTAINED-RELEASE - ORAL

Nifedipine sustained-release is commonly used to treat high blood pressure (hypertension) and chest pain (angina).

Nifedipine sustained-release belongs to a class of drugs called calcium channel blockers. It works by relaxing and widening the blood vessels, which helps to lower blood pressure and improve blood flow to the heart.

Common side effects include headache, dizziness, flushing, swollen ankles or feet, and constipation. More serious side effects may include rapid heartbeat, shortness of breath, and signs of liver problems. It is important to contact a healthcare provider if any severe side effects occur.

Nifedipine sustained-release should be taken orally as directed by your doctor. It is usually recommended to be taken once daily, preferably with a meal. Do not crush or chew the tablet, as it is designed for slow release.

Nifedipine sustained-release may interact with other medications, such as certain antibiotics, antifungal drugs, and medications for high blood pressure or heart conditions. It is important to inform your doctor about all the medications you are currently taking to avoid any potential interactions.

It is important to consult a healthcare provider before taking Nifedipine sustained-release during pregnancy or breastfeeding. They will weigh the potential risks and benefits to determine if it is safe for use.

The onset of action of Nifedipine sustained-release can vary from person to person, but it generally starts to work within 1 to 2 hours after taking the medication.

It is generally advised to avoid alcohol while taking Nifedipine sustained-release, as alcohol can increase the risk of side effects such as dizziness and low blood pressure.

If you miss a dose, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.