NETUPITANT/PALONOSETRON - ORAL

  • Home
  • NETUPITANT/PALONOSETRON - ORAL

NETUPITANT/PALONOSETRON - ORAL

PHONETIC PRONUNCIATION: (net-UE-pi-tant/PAL-oh-NOE-se-tron)

COMMON BRAND NAME(S): Akynzeo

GENERIC NAME(S): netupitant/palonosetron HCl

Uses

USES: This product contains 2 medications: netupitant and palonosetron. It is used to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Netupitant and palonosetron work by blocking natural substances in the body (such as substance P/neurokinin 1, serotonin) that cause vomiting.


How to use NETUPITANT/PALONOSETRON - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking netupitant/palonosetron and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually 1 hour before the start of chemotherapy. Tell your doctor if you vomit or feel nauseated.

Side Effects

SIDE EFFECTS: Headache may occur. If this effect persists or worsens, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. One of the medications in this product (palonosetron) may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking this product, tell your doctor or pharmacist if you are allergic to netupitant or to palonosetron; or to other anti-nausea serotonin blockers (such as ondansetron); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this product passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. This medication can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include flibanserin, lomitapide, among others. Other medications can affect the removal of this product from your body, which may affect how it works. Examples include rifamycins (such as rifampin), St. John's wort, among others. The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

AKYNZEO 300-0.5 MG CAPSULE
AKYNZEO 300-0.5 MG CAPSULE
color
caramel
shape
oblong
imprint
HE1

Reviews

No Reviews Yet


Faq for NETUPITANT/PALONOSETRON - ORAL

Netupitant/Palonosetron is an oral combination medication used to prevent nausea and vomiting caused by chemotherapy treatment.

Netupitant/Palonosetron works by blocking certain chemicals in the body that cause nausea and vomiting. It also works on multiple pathways in the brain to help prevent these symptoms.

Netupitant/Palonosetron is usually taken approximately 1 hour before chemotherapy treatment. It comes in the form of a capsule that should be swallowed whole with water.

Common side effects of Netupitant/Palonosetron include headache, fatigue, constipation, and diarrhea. If any of these side effects persist or worsen, it is important to consult your healthcare provider.

Netupitant/Palonosetron may interact with certain medications, including some antidepressants and anti-seizure drugs. It is important to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.

It is not recommended to use Netupitant/Palonosetron during pregnancy unless the potential benefits outweigh the risks. It is also not known if the medication passes into breast milk, so it is advised to consult with your healthcare provider if you are breastfeeding.

The duration of treatment with Netupitant/Palonosetron will depend on your specific chemotherapy regimen. Your healthcare provider will determine the appropriate duration of usage.

If you miss a dose of Netupitant/Palonosetron, take it as soon as you remember. However, if it is already close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Netupitant/Palonosetron can be taken with or without food. However, some people may experience a decrease in effectiveness when taken on an empty stomach, so it is generally recommended to take it with a meal or a snack.

NETUPITANT/PALONOSETRON - ORAL Pricing Page Get Discount Coupon


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.