NAPROXEN/ESOMEPRAZOLE - ORAL
PHONETIC PRONUNCIATION: (na-PROX-en/ES-oh-MEP-ra-zole)
COMMON BRAND NAME(S): Vimovo
GENERIC NAME(S): naproxen/esomeprazole magnesium
Uses
USES: This medication is used to treat the signs and symptoms of rheumatoid arthritis, osteoarthritis, juvenile idiopathic arthritis, and ankylosing spondylitis when there is a high risk for stomach bleeding/ulcer. This product contains 2 medications: esomeprazole and naproxen. This product should not be used to relieve sudden pain. The naproxen starts to work slower than other naproxen products because of a special coating (delayed-release). If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). It reduces pain, swelling, and joint stiffness. Naproxen can cause stomach ulcers, especially in patients with a history of stomach ulcers. Esomeprazole is a proton pump inhibitor (PPI) that blocks acid production in the stomach. This combination provides the benefits of naproxen and may reduce the risk of ulcers or bleeding that can occur with naproxen use.
How to use NAPROXEN/ESOMEPRAZOLE - ORAL
HOW TO USE: Read the Medication Guide provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually twice daily (in the morning and evening) at least 30 minutes before a meal. Take it with a full glass (8 ounces or 240 milliliters) of water unless your doctor directs you otherwise. Do not lie down for at least 10 minutes after taking this drug. Swallow the tablet whole. Do not break, chew, crush or dissolve the tablet. Doing so can destroy the slow release of the drug and may increase side effects. If needed, you can take antacids while using this medication. The dosage is based on your medical condition and response to treatment. In children, the dosage is also based on weight. To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time. Do not increase your dose, take it more frequently, or take it for longer than prescribed. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. It may take up to 2 weeks of taking this drug until you get the full benefit. Tell your doctor if your condition persists or worsens. The risk of side effects goes up over time. Ask your doctor how long you should take this medication.
Side Effects
Precautions
Interactions
Overdose
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Faq for NAPROXEN/ESOMEPRAZOLE - ORAL
Naproxen/Esomeprazole is a combination medication used to relieve symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It helps reduce pain, inflammation, and swelling in the joints.
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of certain substances in the body that cause pain and inflammation. Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production, helping to protect the stomach from irritation caused by the NSAID.
Common side effects of Naproxen/Esomeprazole include upset stomach, diarrhea, nausea, headache, dizziness, and constipation. If you experience any severe or persistent side effects, contact your doctor.
It is important to inform your doctor about all the medications you are taking, including prescription, over-the-counter, and herbal supplements. Some medications may interact with Naproxen/Esomeprazole, potentially affecting its effectiveness or increasing the risk of side effects.
Naproxen/Esomeprazole is usually taken once daily, with or without food. It should be swallowed whole and should not be crushed, chewed, or dissolved. Follow the dosage and instructions provided by your doctor or read the medication guide for specific guidelines.
Naproxen/Esomeprazole should be avoided during pregnancy, especially in the third trimester, as it may harm the unborn baby. It is not recommended during breastfeeding as small amounts of the medication may pass into breast milk.
The onset of action may vary from person to person, but typically it takes a few hours for Naproxen/Esomeprazole to start providing pain relief. However, it may take several weeks of regular use for maximum benefits to be achieved.
Alcohol should be avoided or limited while taking Naproxen/Esomeprazole, as it can increase the risk of stomach bleeding and irritation. It is best to consult with your doctor about alcohol consumption while on this medication.
If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
Warning
WARNING: Nonsteroidal anti-inflammatory drugs (including naproxen) may rarely increase the risk for a heart attack or stroke. This effect can happen at any time while taking this drug but is more likely if you take it for a long time. The risk may be greater if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes). Do not take this drug right before or after heart bypass surgery (CABG). Also, this drug may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. This can occur without warning symptoms and at any time during treatment. The risk of bleeding is greater in older adults. Esomeprazole decreases the risk of bleeding. Stop taking this medication and get medical help right away if you notice any of the following rare but very serious side effects: chest/jaw/left arm pain, severe dizziness, weakness on one side of the body, vision changes, slurred speech, black stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds. (See also Precautions section.) Talk with your doctor or pharmacist about the risks and benefits of treatment with this medication.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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