NALOXEGOL - ORAL

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NALOXEGOL - ORAL

PHONETIC PRONUNCIATION: (nal-OX-ee-gol)

COMMON BRAND NAME(S): Movantik

GENERIC NAME(S): naloxegol oxalate

Uses

USES: This medication is used to treat constipation caused by narcotic (opiate-type) medications in people with ongoing pain that is not caused by cancer. It blocks the effect of narcotics on the gut without blocking the effect on pain. Naloxegol belongs to a class of drugs known as narcotic antagonists.


How to use NALOXEGOL - ORAL

HOW TO USE: Read the Medication Guide provided by your pharmacist before you start taking naloxegol and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth on an empty stomach at least 1 hour before or 2 hours after a meal, as directed by your doctor, usually once daily in the morning. If you are unable to swallow this medication whole, you may crush the tablets to a powder, mix in 4 ounces (120 milliliters) of water and drink immediately. Refill the glass with another 4 ounces of water, stir the contents and drink it. If you are giving this medication through a tube into the stomach (nasogastric tube), ask you health care professional for detailed instructions on how to properly mix and give it. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Naloxegol is used only for constipation caused by narcotics. Stop using this medication when you stop taking narcotic pain medication unless otherwise directed by your doctor. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. Stop taking other laxatives before you start treatment with naloxegol. Your doctor may direct you to take other laxatives if your condition does not improve after 3 days of treatment with naloxegol. Ask your doctor for more details and follow your doctor's instructions carefully. Tell your doctor if your constipation persists or worsens.

Side Effects

SIDE EFFECTS: Pain in the stomach/abdomen, diarrhea, or gas may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Opiate withdrawal symptoms may occur in some people. Tell your doctor right away if any of these withdrawal symptoms occur: sweating, chills, pain in the stomach/abdomen, diarrhea, yawning, mental/mood changes (such as anxiety/irritability). This drug may rarely cause a serious tear in the stomach or intestinal wall (perforation). If you notice any of the following unlikely but serious side effects, get medical help right away: severe/persistent/worsening pain in the stomach/abdomen, fever, dizziness/fainting, nausea/vomiting. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking naloxegol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: stomach/intestinal blockage, stomach/intestinal ulcers or tumors, bowel disease (such as Crohn's, diverticulitis), kidney disease. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, naloxegol should be used only when clearly needed. This medication may cause opioid withdrawal in a pregnant woman and her unborn baby. Discuss the risks and benefits with your doctor. It is unknown if this medication passes into breast milk. This medication may cause opioid withdrawal in a nursing infant. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Other medications can affect the removal of naloxegol from your body, which may affect how naloxegol works. Examples include azole antifungals (such as ketoconazole, itraconazole), boceprevir, clarithromycin, cobicistat, indinavir, nefazodone, nelfinavir, rifamycins (such as rifampin, rifabutin), ritonavir, tipranavir, among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

MOVANTIK 12.5 MG TABLET
MOVANTIK 12.5 MG TABLET
MOVANTIK 12.5 MG TABLET
color
mauve
shape
oblong
imprint
nGL, 12.5
MOVANTIK 25 MG TABLET
MOVANTIK 25 MG TABLET
MOVANTIK 25 MG TABLET
color
mauve
shape
oblong
imprint
nGL, 25
MOVANTIK 25 MG TABLET
MOVANTIK 25 MG TABLET
MOVANTIK 25 MG TABLET
color
mauve
shape
oblong
imprint
nGL, 25
MOVANTIK 25 MG TABLET
MOVANTIK 25 MG TABLET
MOVANTIK 25 MG TABLET
color
mauve
shape
oblong
imprint
nGL, 25

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Faq for NALOXEGOL - ORAL

Naloxegol is an oral medication that belongs to the class of drugs known as opioid antagonists. It is used to treat constipation caused by opioid medications.

Naloxegol works by binding to opioid receptors in the gut, blocking the effects of opioids on the bowel. This helps to alleviate constipation caused by opioids without affecting the pain-relieving effects of the opioid medication.

Naloxegol is usually taken once daily, with or without food. It is important to follow the dosage instructions provided by your healthcare provider. Do not exceed the recommended dose.

The most common side effects of naloxegol include stomach pain, diarrhea, nausea, vomiting, headache, and flatulence. If any of these side effects become severe or persistent, it is important to consult your healthcare provider.

No, naloxegol is specifically indicated for people who suffer from constipation caused by opioid medications. It is not recommended for use in individuals who do not take opioids.

It is important to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Naloxegol may interact with certain medications, including opioids, and precautions should be taken to avoid potential interactions.

Naloxegol may start working within one to two days of starting the medication. However, individual response may vary, and it could take longer for some individuals to experience relief from constipation.

The safety of naloxegol during pregnancy or breastfeeding has not been well studied. It is important to consult your healthcare provider before using this medication if you are pregnant or breastfeeding.

Naloxegol has not been studied in children and is not recommended for use in individuals under 18 years of age.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.