MIGLUSTAT - ORAL

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MIGLUSTAT - ORAL

PHONETIC PRONUNCIATION: (mi-GLOO-stat)

COMMON BRAND NAME(S): Zavesca

GENERIC NAME(S): miglustat

Uses

USES: Miglustat is used for the long-term treatment of a certain rare genetic problem (Gaucher's disease). It works by decreasing the amount of a certain natural fatty substance (glucosylceramide) that builds up due to this condition. This can help improve symptoms of Gaucher's disease, such as tiredness, pain in the joints/bones, and a swollen liver or spleen.


How to use MIGLUSTAT - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking miglustat and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually 3 times a day. The dosage is based on your medical condition and response to treatment. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Tell your doctor if your condition does not improve or if it worsens.

Side Effects

SIDE EFFECTS: Nausea, vomiting, stomach/abdominal pain, gas, diarrhea, weight loss, headache, muscle cramps, dizziness, or weakness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To reduce diarrhea, your doctor may tell you to take miglustat between meals, recommend that you change your diet to avoid high-carbohydrate foods, or prescribe a drug (such as loperamide) to treat diarrhea. Talk to your doctor or pharmacist for more details. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: numbness/tingling/weakness/pain of the hands or feet, new/worsening shaking or tremor of the hands, vision changes, new/worsening bruising/bleeding. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking miglustat, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, numbness/tingling of the hands/feet, stomach/intestinal problems (such as inflammatory bowel disease). This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

MIGLUSTAT 100 MG CAPSULE
MIGLUSTAT 100 MG CAPSULE
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OGT 918, 100
MIGLUSTAT 100 MG CAPSULE
MIGLUSTAT 100 MG CAPSULE
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white
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oblong
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OGT 918, 100
MIGLUSTAT 100 MG CAPSULE
MIGLUSTAT 100 MG CAPSULE
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AMG, 310
ZAVESCA 100 MG CAPSULE
ZAVESCA 100 MG CAPSULE
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white
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OGT 918, 100
ZAVESCA 100 MG CAPSULE
ZAVESCA 100 MG CAPSULE
color
white
shape
oblong
imprint
OGT 918, 100

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Faq for MIGLUSTAT - ORAL

Miglustat is an oral medication used to treat type 1 Gaucher disease, a rare genetic disorder that affects the body's ability to break down certain fats. It is also approved for the treatment of Niemann-Pick disease type C, another rare genetic disorder.

Miglustat works by inhibiting the enzyme glucosylceramide synthase, which reduces the production of glucosylceramide, a fatty substance that accumulates in certain cells of individuals with type 1 Gaucher disease and Niemann-Pick disease type C. By decreasing the production of this substance, Miglustat slows down the progression of these diseases.

Common side effects of Miglustat may include diarrhea, weight loss, abdominal pain, flatulence, tremor, headache, and peripheral neuropathy. It is important to discuss any potential side effects with your healthcare provider.

Miglustat is taken orally, typically three times a day with meals. The exact dosage and duration of treatment will depend on the individual's condition and the healthcare provider's recommendation. It is important to follow the prescribed dosing instructions carefully.

Miglustat is not a cure for these diseases, but it can help slow down their progression and manage specific symptoms. It is important to continue taking Miglustat as prescribed by your healthcare provider, even if you start feeling better.

Taking Miglustat with food can help reduce certain side effects, such as gastrointestinal symptoms. Your healthcare provider may also recommend a specific diet or nutritional supplements to support your overall health while taking this medication. It is important to follow any dietary restrictions or recommendations provided by your healthcare provider.

It is important to inform your healthcare provider about all the medications, vitamins, and supplements you are taking before starting Miglustat. Some medications may interact with Miglustat, affecting its effectiveness or increasing the risk of side effects. Your healthcare provider will be able to determine if any adjustments need to be made to your current medication regimen.

Regular check-ups and monitoring are essential while taking Miglustat to assess its effectiveness and monitor for any potential side effects. Your healthcare provider will determine the frequency of your medical appointments based on your individual needs.

It is important to discuss the risks and benefits of using Miglustat during pregnancy or while breastfeeding with your healthcare provider. Miglustat has been associated with potential harm to the fetus in animal studies, and it can also pass into breast milk. Your healthcare provider will determine whether the potential benefits outweigh the potential risks in your specific situation.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.