MIDOSTAURIN - ORAL
PHONETIC PRONUNCIATION: (MYE-doe-STAW-rin)
COMMON BRAND NAME(S): Rydapt
GENERIC NAME(S): midostaurin
Uses
USES: Midostaurin is used to treat certain types of blood cell cancer (acute myeloid leukemia-AML, mast cell leukemia-MCL) or an immune system disorder (mastocytosis). It works by slowing or stopping the growth of cancer cells and certain immune system cells (mast cells).
How to use MIDOSTAURIN - ORAL
HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking midostaurin and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with food as directed by your doctor, usually twice daily (every 12 hours). Swallow the capsules whole. Do not open or crush the capsules. The dosage is based on your medical condition and response to treatment. For certain conditions, you may not need to take this medication every day (for example, some people are directed to take the medication for 2 weeks, then stop for 2 weeks). Follow your doctor's instructions carefully. Your doctor should instruct you to take other medications to prevent nausea and vomiting. Take those medications as directed. If you vomit after taking a dose, do not take another dose at that time. Take your next dose on your usual dosing schedule. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.
Side Effects
Precautions
Interactions
Overdose
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Faq for MIDOSTAURIN - ORAL
Midostaurin is used to treat a certain type of blood cancer called acute myeloid leukemia (AML). It is specifically used in patients with a specific genetic mutation called FLT3.
Midostaurin works by inhibiting certain proteins in cancer cells, including FLT
Midostaurin is taken orally, usually with food, twice a day. It is important to follow your doctor's instructions and take the medicine at the same time each day.
Common side effects of midostaurin include nausea, vomiting, diarrhea, stomach pain, headache, dizziness, fever, and rash. It is important to report any severe or persistent side effects to your doctor.
It is generally recommended to avoid alcohol consumption while taking midostaurin, as it may increase the risk of side effects and interfere with the effectiveness of the medication. It's best to discuss this with your doctor.
Midostaurin may interact with certain medications, including strong CYP3A4 inhibitors and inducers, anticoagulants, and antiplatelet drugs. It's important to inform your doctor about all the medications you are taking to avoid any potential interactions.
The duration of midostaurin treatment is determined by your doctor based on your individual condition. It is usually taken in cycles, with periods of treatment and rest. It's important to follow your doctor's instructions regarding the duration of treatment.
Midostaurin may harm the unborn baby, so it is not recommended for use during pregnancy. It is also not known if the drug passes into breast milk, so breastfeeding while taking midostaurin is discouraged. It's essential to discuss the potential risks and benefits with your doctor.
If you miss a dose of midostaurin, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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