METHYCLOTHIAZIDE - ORAL

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METHYCLOTHIAZIDE - ORAL

PHONETIC PRONUNCIATION: (meth-i-kloe-THIGH-uh-zide)

COMMON BRAND NAME(S): Enduron

GENERIC NAME(S): methyclothiazide

Uses

USES: This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Methyclothiazide is a "water pill" (diuretic) that causes your body to get rid of extra salt and water. This increases the amount of urine you make. This medication also reduces extra fluid in the body (edema) caused by conditions such as congestive heart failure, liver disease, and kidney disease. Getting rid of extra water helps to reduce fluid in the lungs so that you can breathe easier. It also helps to decrease swelling of the arms, legs, and stomach/abdomen.


How to use METHYCLOTHIAZIDE - ORAL

HOW TO USE: Take this medication by mouth with or without food, usually once daily or as directed by your doctor. It is best to avoid taking this medication within 4 hours of your bedtime to avoid having to get up to urinate. Consult your doctor or pharmacist if you have questions about your dosing schedule. The dosage is based on your medical condition and response to therapy. The manufacturer recommends that you do not take more than 10 milligrams as a single daily dose to treat edema or more than 5 milligrams daily to treat high blood pressure. Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day or as prescribed. Do not increase your dose, skip doses, or stop taking this medication unless directed by your doctor. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. For the treatment of high blood pressure, it may take up to several weeks before the full benefit of this drug takes effect. Cholestyramine and colestipol can decrease the absorption of this medication by your body. If you are taking either of these drugs, separate them from methyclothiazide by at least 4 hours. Inform your doctor if your condition does not improve or if it worsens (e.g., swelling increases, your routine blood pressure readings increase).

Side Effects

SIDE EFFECTS: Dizziness, lightheadedness, headache, blurred vision, loss of appetite, stomach upset, diarrhea, or constipation may occur as your body adjusts to the medication. You may also experience decreased sexual ability. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may cause a loss of too much body water (dehydration) and salt/minerals. Tell your doctor right away if you have any of these unlikely but serious symptoms of dehydration or mineral loss: very dry mouth, thirst, muscle cramps, weakness, fast/irregular heartbeat, nausea, vomiting, severe dizziness, unusual drowsiness, fainting, confusion, seizures. Tell your doctor right away if any of these unlikely but serious side effects occur: numbness/tingling of the arms/legs, joint pain (e.g., big toe pain). Tell your doctor right away if any of these rare but very serious side effects occur: signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, stomach/abdominal pain, persistent nausea/vomiting, unusual/persistent tiredness, yellowing eyes/skin, dark urine, signs of kidney problems (such as change in the amount of urine). Get medical help right away if you have any very serious side effects, including: decrease in vision, eye pain. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking methyclothiazide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe kidney disease (inability to make urine). Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, untreated salt/mineral imbalance (e.g., imbalance of sodium, potassium, calcium, magnesium), loss of too much body water (dehydration), gout, lupus, certain recent nerve surgery (sympathectomy). If you have diabetes, methyclothiazide may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet. This drug may reduce the potassium levels in your blood. Ask your doctor about increasing the amount of potassium in your diet (e.g., bananas, orange juice) or about using a salt substitute containing potassium. A potassium supplement may be prescribed by your doctor. This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. Before having surgery, tell your doctor or dentist that you are taking this medication. This drug may make you dizzy or blur your vision. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Significant loss of body water from too much sweating, vomiting, or diarrhea can also lower your blood pressure and worsen dizziness. Drink plenty of fluids to prevent these effects and dehydration. If you are on restricted fluid intake, consult your doctor for further instructions. Contact your doctor if you are unable to drink fluids or if you have persistent diarrhea/vomiting. Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, the elderly may be more sensitive to the effects of this drug, especially dizziness. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: See also the How to Use section. Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first. This drug should not be used with the following medications because very serious interactions may occur: cisapride, dofetilide. If you are currently using any of these medications, tell your doctor or pharmacist before starting methyclothiazide. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: diazoxide, digoxin, lithium, nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, indomethacin). Some products have ingredients that could raise your blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). This product can affect the results of certain lab tests. Make sure laboratory personnel and all your doctors know you use this drug. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, severe weakness, fainting.

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Faq for METHYCLOTHIAZIDE - ORAL

Methyclothiazide is an oral medication belonging to the class of drugs known as thiazide diuretics. It is primarily used to treat high blood pressure (hypertension) by helping the body eliminate excess water and salt.

Methyclothiazide works by increasing the amount of urine produced by the kidneys, which helps to reduce fluid retention and lower blood pressure. It does this by blocking the reabsorption of sodium and chloride in the kidneys.

Common side effects of methyclothiazide include increased urination, dizziness, lightheadedness, nausea, stomach upset, headache, and muscle cramps. These side effects are usually mild and go away on their own.

While rare, some serious side effects may occur with methyclothiazide. These can include severe allergic reactions, electrolyte imbalances, kidney problems, liver dysfunction, and changes in blood sugar levels. It is important to seek immediate medical attention if you experience any severe or persistent side effects.

Methyclothiazide is not recommended for use during pregnancy as it may harm the unborn baby. It is also not recommended for use while breastfeeding as it may pass into breast milk and harm the nursing infant. Consult with your doctor for alternative medications if you are pregnant or breastfeeding.

Methyclothiazide may interact with certain medications or substances, including other blood pressure medications, nonsteroidal anti-inflammatory drugs (NSAIDs), lithium, corticosteroids, and some cholesterol-lowering drugs. Be sure to inform your healthcare provider about all the medications, supplements, and herbal products you are taking.

Methyclothiazide is usually taken once a day, either in the morning or as directed by your doctor. It can be taken with or without food. Follow the instructions provided by your doctor or pharmacist.

If you miss a dose of methyclothiazide, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.

Methyclothiazide may start working within 1 to 2 hours after taking it. However, it may take several weeks for the full effects of the medication to be noticeable. Continue taking it as directed even if you feel well.

- Methyclothiazide is primarily used to treat high blood pressure (hypertension) and to reduce excessive fluid buildup in the body (edema) caused by conditions such as heart failure or liver disease.

- Methyclothiazide may interact with other medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), lithium, corticosteroids, diabetes medications, and certain heart medications. It is essential to inform your doctor or pharmacist about all the medications you are currently taking to avoid any potential interactions.

- Methyclothiazide should be used during pregnancy only if clearly needed and under the guidance of a healthcare professional. It is not recommended for use during breastfeeding as it may pass into breast milk.

- It is generally not recommended to stop taking methyclothiazide suddenly without consulting your doctor. Abruptly stopping the medication may lead to a significant increase in blood pressure or fluid retention.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.