MESNA - ORAL

MESNA - ORAL

PHONETIC PRONUNCIATION: (MESS-na)

COMMON BRAND NAME(S): Mesnex

GENERIC NAME(S): mesna

Uses

USES: This medication is used to reduce the risk of bleeding in the bladder (hemorrhagic cystitis), which is a very serious side effect of treatment with a cancer chemotherapy drug called ifosfamide. Mesna helps to protect the lining of the bladder against damage from ifosfamide. The body breaks down ifosfamide to form a product that can harm the bladder, and mesna works by making this product less harmful. However, mesna does not change ifosfamide's anti-cancer effects.


How to use MESNA - ORAL

HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start taking mesna and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth. Follow the dosing schedule as directed by your doctor. Dosage is based on your body size and your dose of ifosfamide (or cyclophosphamide). While taking this medication, drink at least a quart (4 cups or 1 liter) of liquid each day unless directed otherwise by your doctor. Doing so will also help to reduce the bladder side effects from ifosfamide. Tell your doctor right away if you vomit within 2 hours of taking a dose. Your doctor will determine if you should repeat the dose or receive mesna by injection into a vein. Mesna is very effective in reducing the risk of hemorrhagic cystitis in most patients. However, it may not work in a small number of patients. Therefore, tell your doctor right away if you notice that your urine is pink, red, or bloody.

Side Effects

SIDE EFFECTS: Headache, flushing, dizziness, drowsiness, nausea, vomiting, loss of appetite, diarrhea, constipation, sensitive skin, or flu-like symptoms (such as sore throat, cough, body aches) may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: fast heartbeat, swelling ankles/feet, muscle weakness. Get medical help right away if you have any very serious side effects, including: chest pain. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking mesna, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: overactive immune system diseases (autoimmune disorders) that may increase your risk for a mesna allergy (e.g., rheumatoid arthritis, lupus, nephritis). This drug may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Kidney function declines as you grow older. This medication is removed by the kidneys. The elderly may be more sensitive to the effects of this drug. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Since this medication is given with a cancer chemotherapy drug, breast-feeding while using mesna is not recommended. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use. This medication may interfere with a certain laboratory test (for urinary ketones), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

MESNEX 400 MG TABLET
MESNEX 400 MG TABLET
MESNEX 400 MG TABLET
color
white
shape
oblong
imprint
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Faq for MESNA - ORAL

MESNA is used to reduce side effects caused by certain medications, particularly chemotherapy drugs.

MESNA works by detoxifying certain harmful substances that are produced during the breakdown of chemotherapy medications in the body.

Common side effects of MESNA include nausea, vomiting, diarrhea, headache, dizziness, and fatigue.

MESNA is usually taken as a tablet or solution by mouth, as directed by your doctor. It is important to follow the dosage instructions carefully and take it at the same time each day.

Yes, it is important to inform your doctor if you have a history of kidney problems, liver problems, or if you are pregnant or breastfeeding. MESNA may interact with certain medications, so it is essential to inform your doctor about all the medications you are taking.

It is generally recommended to avoid alcohol while taking MESNA, as alcohol can worsen certain side effects of the medication.

MESNA can be used in children, but the dosage and administration should be determined by a healthcare professional.

The duration of MESNA treatment will depend on your specific condition and the chemotherapy drugs you are receiving. Your doctor will provide guidance on the duration of treatment.

If you miss a dose of MESNA, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.