LUMACAFTOR/IVACAFTOR - ORAL
PHONETIC PRONUNCIATION: (LOO-ma-KAF-tor/EYE-va-KAF-tor)
COMMON BRAND NAME(S): Orkambi
GENERIC NAME(S): lumacaftor/ivacaftor
Uses
USES: This medication is a combination of 2 medications: lumacaftor and ivacaftor. It is used to treat cystic fibrosis in certain people (those with 2 copies of an abnormal "CFTR" gene). It may help to improve breathing, reduce the risk of lung infections, and improve weight gain.
How to use LUMACAFTOR/IVACAFTOR - ORAL
HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking lumacaftor/ivacaftor and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually twice daily (12 hours apart). For the best effect, take it with food that contains fat (such as eggs, avocados, cheese, nuts, butter, peanut butter). The dosage is based on your age, medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Tell your doctor if your condition does not get better or if it gets worse.
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Faq for LUMACAFTOR/IVACAFTOR - ORAL
Lumacaftor/Ivacaftor is used to treat cystic fibrosis in patients aged 6 years and older who have a specific genetic mutation.
Lumacaftor/Ivacaftor is a combination medication that helps improve lung function in cystic fibrosis patients by increasing the amount of functional protein at the surface of the cells in the lungs.
Common side effects of Lumacaftor/Ivacaftor may include respiratory symptoms (such as shortness of breath and chest discomfort), increased respiratory infections, sinus congestion, nausea, diarrhea, fatigue, and abnormal liver function tests.
Lumacaftor/Ivacaftor may start showing improvements in lung function within a few weeks of starting treatment. However, the full effects may take several months to be noticeable.
Lumacaftor/Ivacaftor is approved for use in patients aged 6 years and older who have the specific genetic mutation that the medication targets. It is not recommended for use in younger children.
Lumacaftor/Ivacaftor is not a cure for cystic fibrosis. It is a medication that helps improve lung function and reduce symptoms in patients with this condition.
Lumacaftor/Ivacaftor should be taken exactly as prescribed by a healthcare professional. It is usually taken twice daily with fat-containing food, as this improves the absorption of the medication.
Lumacaftor/Ivacaftor can be used in combination with other medications prescribed for cystic fibrosis. However, it is important to consult with a healthcare professional and disclose all other medications being taken to avoid potential interactions.
If a dose of Lumacaftor/Ivacaftor is missed, it should be taken as soon as remembered. However, if it is close to the time of the next scheduled dose, the missed dose should be skipped and the regular dosing schedule resumed.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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