Lomitapide is a medication that belongs to a class of drugs called microsomal triglyceride transfer protein inhibitors. It is used to treat a rare genetic condition called homozygous familial hypercholesterolemia (HoFH) that causes extremely high levels of cholesterol in the blood.

Lomitapide works by reducing the production of LDL cholesterol, also known as "bad cholesterol," in the liver. It inhibits the microsomal triglyceride transfer protein, which is involved in the assembly and secretion of LDL particles. By decreasing LDL cholesterol levels, lomitapide helps to lower the risk of cardiovascular events associated with HoFH.

Lomitapide is available in capsule form and should be taken orally once daily with a low-fat meal. It is crucial to follow a low-fat diet while taking this medication to further reduce the risk of liver problems. Your doctor will determine the appropriate dosage based on your specific condition.

Common side effects of lomitapide may include diarrhea, nausea, vomiting, abdominal pain, indigestion, bloating, and gas. These side effects usually improve over time as your body adjusts to the medication. However, if they persist or become bothersome, it is essential to inform your doctor.

Yes, lomitapide can cause serious liver problems. It may increase liver enzyme levels and cause liver fat accumulation, which can lead to liver inflammation or failure. Regular liver function tests are necessary to monitor liver health during treatment. Other serious side effects may include gastrointestinal problems, vitamin deficiency, and pregnancy complications.

No, lomitapide is contraindicated during pregnancy due to the risk of serious harm to the fetus. It is also not recommended while breastfeeding because it may pass into breast milk and cause harm to the nursing infant. Effective contraception should be used during treatment with lomitapide to prevent pregnancy.

Lomitapide is an oral medication used to treat a certain genetic disorder called homozygous familial hypercholesterolemia (HoFH), which causes high levels of cholesterol in the blood.

Lomitapide works by inhibiting the production of low-density lipoprotein (LDL) cholesterol, also known as the "bad" cholesterol, in the liver. It reduces the amount of LDL cholesterol that is released into the bloodstream.

Common side effects of Lomitapide may include diarrhea, nausea, vomiting, stomach pain, indigestion, fatigue, and liver abnormalities. These side effects can be managed with proper monitoring and dosing adjustments.

Lomitapide should be taken exactly as prescribed by a healthcare professional. It is usually taken once daily, with or without food. It is important to follow a low-fat diet and avoid grapefruit and grapefruit juice while taking Lomitapide.

No, Lomitapide should not be used during pregnancy as it may harm the developing baby. It is also not recommended during breastfeeding as it can pass into breast milk.

Lomitapide may start working within a few weeks, but it may take several months to see the full effects on cholesterol levels. Regular blood tests will be done to monitor cholesterol levels and determine the effectiveness of the medication.

Yes, Lomitapide can interact with other medications, including certain cholesterol-lowering drugs, antifungal medications, HIV medications, and other drugs that may affect liver enzymes. It is important to inform your healthcare provider about all the medications you are taking to avoid potential interactions.

No, Lomitapide is not a cure for high cholesterol. It is a treatment that helps to lower LDL cholesterol levels in people with HoFH. It should be used in combination with other cholesterol-lowering measures, such as a low-fat diet and exercise.

If you accidentally miss a dose of Lomitapide, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.