LETROZOLE - ORAL

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LETROZOLE - ORAL

PHONETIC PRONUNCIATION: (LET-tro-zole)

COMMON BRAND NAME(S): Femara

GENERIC NAME(S): letrozole

Uses

USES: This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.


How to use LETROZOLE - ORAL

HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start using letrozole and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth, usually once daily with or without food or as directed by your doctor. Dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Since this drug can be absorbed through the skin and lungs, women who are pregnant should not handle this medication or breathe the dust from the tablets. (See also Precautions section.) Inform your doctor right away if your condition worsens (such as you get new breast lumps).

Side Effects

SIDE EFFECTS: Hot flashes, hair loss, joint/bone/muscle pain, tiredness, unusual sweating, nausea, diarrhea, dizziness, and trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: bone fractures, mental/mood changes (such as depression, anxiety), swelling of arms/legs, blurred vision, persistent nausea/vomiting, unusual tiredness, dark urine, yellowing eyes/skin.. This medication (and cancer) may rarely cause serious problems from blood clots (such as heart attack or stroke). Get medical help right away if you experience: sudden shortness of breath, chest/jaw/left arm pain, confusion, coughing up blood, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, tingling/weakness/numbness in the arms/legs, slurred speech, weakness on one side of the body, vision changes, sudden/severe headache. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat/neck), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking letrozole, tell your doctor or pharmacist if you are allergic to it; or to anastrozole; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: high blood fats (cholesterol), bone problems (such as osteopenia, osteoporosis), stroke or blood clots, heart disease (such as chest pain, heart attack, heart failure), high blood pressure, kidney problems, liver problems. This drug may make you dizzy or tired or rarely blur your vision. Alcohol or marijuana can make you more dizzy or tired. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication must not be used during pregnancy. It may harm an unborn baby. Letrozole is used mainly in women after menopause. If you have recently gone through menopause, discuss the need for use of reliable forms of birth control while taking this medication and for 3 weeks after stopping treatment with your doctor. Do not use birth control products containing estrogen. Consult your doctor for more details. If you become pregnant or think you may be pregnant, tell your doctor right away. (See also How to Use section.) It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug and for at least 3 weeks after stopping treatment is not recommended. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: estrogens (such as ethinyl estradiol, conjugated estrogens), estrogen blockers (such as anastrozole, tamoxifen).

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

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Faq for LETROZOLE - ORAL

Letrozole is an oral medication commonly used for the treatment of breast cancer in postmenopausal women. It belongs to a class of drugs called aromatase inhibitors.

Letrozole works by inhibiting the production of estrogen in the body. It blocks the enzyme aromatase, which is responsible for converting androgens into estrogen. By reducing estrogen levels, it helps to slow down or halt the growth of breast cancer cells.

Common side effects of Letrozole include hot flashes, joint pain, muscle pain, fatigue, increased sweating, nausea, and dizziness. These side effects are usually mild and temporary.

Letrozole is usually taken once daily with or without food. It is important to take it at the same time every day. The dosage and duration of treatment will be determined by your doctor.

Yes, Letrozole is sometimes prescribed off-label for fertility treatment. It can help stimulate the ovaries and promote ovulation in women who have difficulty conceiving. However, it should only be used under the guidance of a fertility specialist.

Patients with a known allergy to Letrozole or any of its ingredients should not take this medication. It is also not recommended for use during pregnancy or breastfeeding. Letrozole may cause harm to an unborn baby or pass into breast milk.

Letrozole may interact with certain medications, such as hormone replacement therapy, tamoxifen, and other aromatase inhibitors. It is important to inform your doctor about all the medications you are taking, including prescription, over-the-counter drugs, and herbal supplements.

The duration of Letrozole treatment will depend on your specific medical condition and response to the medication. It is typically prescribed for a period of 5 to 10 years for breast cancer treatment. Fertility treatment may involve multiple cycles.

Letrozole has been associated with a potential increased risk of bone loss or osteoporosis. Your doctor may recommend regular bone density scans and prescribe calcium and vitamin D supplements to minimize this risk.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.