LETERMOVIR - ORAL

LETERMOVIR - ORAL

PHONETIC PRONUNCIATION: (le-TERM-oh-vir)

COMMON BRAND NAME(S): Prevymis

GENERIC NAME(S): letermovir

Uses

USES: This medication is used to prevent disease caused by a virus called cytomegalovirus (CMV) in people who have received a bone marrow transplant. CMV disease can lead to serious infections in the body, including an infection in the eye, called CMV retinitis, that can cause blindness. Letermovir is an anti-viral drug. It works by stopping the growth of the virus.


How to use LETERMOVIR - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking letermovir and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food, as directed by your doctor, usually once daily. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Swallow the tablet whole. Do not crush or chew because the drug has a bitter taste. For the best effect, take this medication at evenly spaced times. To help you remember, take this medication at the same time every day. Continue to take this medication until the full prescribed amount is finished. Stopping the medication too early may result in an infection.

Side Effects

SIDE EFFECTS: Nausea, diarrhea, vomiting, swelling ankles/feet, cough, or headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: fast/irregular heartbeat. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking letermovir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. This medication can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include ergot alkaloids (such as ergotamine, dihydroergotamine), flibanserin, pimozide, certain statin drugs (such as pitavastatin, simvastatin), among others. Other medications can affect the removal of letermovir from your body, which may affect how letermovir works. Examples include rifampin, among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for LETERMOVIR - ORAL

Letermovir is a medication that is taken orally and is used to prevent cytomegalovirus (CMV) infection in adult patients who have received an allogeneic hematopoietic stem cell transplant.

Letermovir belongs to a class of drugs known as CMV DNA terminase complex inhibitors. It works by preventing the replication, or multiplication, of CMV in the body.

Letermovir is taken as a tablet by mouth, usually once a day. It should be taken with food to enhance absorption. The exact dosing instructions will be provided by your healthcare provider.

The common side effects of Letermovir include nausea, diarrhea, vomiting, headache, cough, and fatigue. It is important to inform your healthcare provider if you experience any severe or persistent side effects.

Letermovir can interact with certain medications, so it is important to inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products.

The duration of Letermovir treatment will be determined by your healthcare provider. It is important to follow their instructions and complete the full course of treatment, even if you start feeling better.

Letermovir is not recommended during pregnancy unless the potential benefits outweigh the risks. It is also not known if Letermovir passes into breast milk, so caution is advised while breastfeeding.

If you miss a dose of Letermovir, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Letermovir is not a cure for CMV infection. It is used to prevent CMV infection in high-risk patients who have undergone a specific type of transplant. It is important to continue taking Letermovir as prescribed by your healthcare provider.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.