ISOSORBIDE DINITRATE SUSTAINED-ACTION - ORAL

ISOSORBIDE DINITRATE SUSTAINED-ACTION - ORAL

PHONETIC PRONUNCIATION: (EYE-soe-SOR-bide dye-NYE-trate)

COMMON BRAND NAME(S): Dilatrate-SR, Isochron

GENERIC NAME(S): isosorbide dinitrate

Uses

USES: Isosorbide dinitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). This medication belongs to a class of drugs known as nitrates. It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medication will not relieve chest pain once it occurs. It is also not intended to be taken just before physical activities (such as exercise, sexual activity) to prevent chest pain. Other medications may be needed in these situations. Consult your doctor for more details.


How to use ISOSORBIDE DINITRATE SUSTAINED-ACTION - ORAL

HOW TO USE: Take this medication by mouth, usually once or twice daily or as directed by your doctor. If you are using this medication twice daily, take the first dose of the day when you wake up, then take the second dose 6 to 7 hours later. It is important to take the drug at the same times each day. Do not change the dosing times unless directed by your doctor. Swallow the capsules whole. Do not crush or chew the capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Use this medication regularly to get the most benefit from it. Do not suddenly stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Tell your doctor if this medication stops working well (for example, you have worsening chest pain or it occurs more often).

Side Effects

SIDE EFFECTS: Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Headache is often a sign that this medication is working. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). If the headaches continue or become severe, tell your doctor promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, fast/irregular/pounding heartbeat. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide mononitrate, nitroglycerin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: recent head injury, frequent stomach cramping/watery stools/severe diarrhea (GI hypermotility), lack of proper absorption of nutrients (malabsorption). Before using this medication, tell your doctor or pharmacist your medical history, especially of: anemia, low blood pressure, loss of too much body water (dehydration), other heart problems (such as recent heart attack). This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist that you are using this medication. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this medication passes into breast milk or if it may harm a nursing infant. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), certain drugs to treat migraine headaches (ergot alkaloids such as ergotamine), riociguat. Some products have ingredients that could worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Isosorbide dinitrate is very similar to isosorbide mononitrate. Do not use medications containing isosorbide mononitrate while using isosorbide dinitrate. This medication may interfere with certain laboratory tests (including blood cholesterol levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips.

Images

ISOCHRON 40 MG TABLET SA

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peach
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3613 IL

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pink
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AP, 0920
ISOSORBIDE DINITR ER 40 MG TAB

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peach
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3613 IL

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Faq for ISOSORBIDE DINITRATE SUSTAINED-ACTION - ORAL

Isosorbide Dinitrate Sustained-Action is used to prevent and relieve chest pain (angina) in patients with coronary artery disease.

It works by relaxing and widening blood vessels, allowing more oxygen and blood flow to the heart. This helps relieve chest pain and prevent angina attacks.

The dosage varies depending on the individual and their medical condition. It is important to follow the instructions given by your doctor or pharmacist. Usually, the recommended starting dose is 20 mg, taken once or twice daily.

This medication can be taken with or without food. However, it is recommended to take it on an empty stomach for better absorption.

Some common side effects include headache, dizziness, lightheadedness, flushing, and nausea. These side effects are usually temporary and may subside with continued use. Contact your doctor if they persist or worsen.

It is important to inform your doctor about any existing medical conditions, especially low blood pressure, liver disease, or heart problems. Isosorbide Dinitrate Sustained-Action may interact with certain medications, so it is crucial to provide a complete list of all medications, supplements, and herbal products you are taking.

It is not recommended to use Isosorbide Dinitrate Sustained-Action during pregnancy or breastfeeding unless specifically prescribed by a doctor. It is important to discuss the potential risks and benefits with your healthcare provider.

If you miss a dose, take it as soon as you remember. However, if it is close to the next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.