ISAVUCONAZONIUM - ORAL

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ISAVUCONAZONIUM - ORAL

PHONETIC PRONUNCIATION: (EYE-sa-vue-KOE-na-ZOE-nee-um)

COMMON BRAND NAME(S): Cresemba

GENERIC NAME(S): isavuconazonium sulfate

Uses

USES: This medication is used to treat certain serious fungal infections. This medication is known as an azole antifungal. It works by stopping the growth of fungi.


How to use ISAVUCONAZONIUM - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually every 8 hours for the first 6 doses (48 hours). Then 12 to 24 hours after the first 6 doses, take this medication once daily. The manufacturer directs not to chew, crush, dissolve, or open the capsule before taking it. However, many similar drugs (immediate-release capsules) can be chewed, crushed, dissolved, or opened. Follow your doctor's directions on how to take this medication. This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection. Tell your doctor if your condition does not improve or if it worsens.

Side Effects

SIDE EFFECTS: Dizziness, nausea, vomiting, diarrhea, headache, constipation, cough, and trouble sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: muscle cramps/spasms, weakness, irregular heartbeat, swelling hands/ankles/feet, back pain, mental/mood changes (such as confusion, anxiety). Get medical help right away if you have any very serious side effects, including: fast/irregular/pounding heartbeat, chest pain, fainting, signs of kidney problems (such as change in the amount of urine), seizures. Isavuconazonium may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, including: persistent nausea/vomiting, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine. Isavuconazonium can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Therefore, tell your doctor right away if you develop any rash. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking isavuconazonium, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, family history of certain heart problems (short QT syndrome, abnormal heart rate/rhythm). This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication is not recommended for use during pregnancy. It may harm an unborn baby. Consult your doctor for more details. It is unknown if this drug passes into breast milk. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. This medication can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include bosutinib, lomitapide, simeprevir, tolvaptan, among others. Other medications can affect the removal of isavuconazonium from your body, which may affect how isavuconazonium works. Examples include certain azole antifungals (such as itraconazole, ketoconazole), certain drugs used to treat chronic hepatitis C (boceprevir, telaprevir), certain HIV protease inhibitors (such as nelfinavir, saquinavir), nefazodone, certain rifamycins (such as rifabutin, rifampin), certain drugs used to treat seizures (such as carbamazepine, phenobarbital), St. John's wort, among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

CRESEMBA 186 MG CAPSULE
CRESEMBA 186 MG CAPSULE
color
swedish orange
shape
oblong
imprint
ISA, logo
CRESEMBA 186 MG CAPSULE
CRESEMBA 186 MG CAPSULE
color
swedish orange
shape
oblong
imprint
logo, 766

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Faq for ISAVUCONAZONIUM - ORAL

Isavuconazonium oral is used to treat certain fungal infections, including invasive fungal infections caused by Aspergillus or Mucorales.

Isavuconazonium oral works by inhibiting the growth of fungi, thus preventing the infection from spreading and helping the body's immune system to fight off the infection.

The common side effects of Isavuconazonium oral include nausea, vomiting, diarrhea, headache, and abnormal liver function tests. It is important to consult a healthcare professional for a complete list of possible side effects.

Isavuconazonium oral is usually taken with or without food, as directed by the healthcare professional. It is important to follow the prescribed dosage and duration of treatment for the best results.

Yes, Isavuconazonium oral may interact with certain medications, including certain anticoagulants, anticonvulsants, and some anti-infective agents. It is crucial to inform the healthcare professional about all the medications, supplements, and herbal products you are taking before starting Isavuconazonium oral.

The safety of Isavuconazonium oral during pregnancy and breastfeeding is not well established. It is recommended to discuss the potential risks and benefits with a healthcare professional before using this medication in these situations.

The response to Isavuconazonium oral can vary depending on the individual and the severity of the fungal infection. It is important to continue taking the medication as prescribed by the healthcare professional, even if symptoms improve, to ensure complete treatment.

The use of Isavuconazonium oral in children has not been extensively studied. The dosage and safety of this medication for pediatric patients may vary, and it is essential to consult a healthcare professional for appropriate guidance.

If you miss a dose of Isavuconazonium oral, take it as soon as you remember. However, if it is close to the time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for the missed one.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.