HYDROXYPROGESTERONE CAPROATE - INJECTION

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HYDROXYPROGESTERONE CAPROATE - INJECTION

PHONETIC PRONUNCIATION: (hye-DROX-ee-proe-JES-ter-one KAP-roe-ate)

COMMON BRAND NAME(S): Makena

GENERIC NAME(S): hydroxyprogesterone caproate/PF

Uses

USES: This medication is used in women who are pregnant with a single baby, and who have delivered a baby too early (preterm) in the past. It is used to help lower the risk of having a preterm baby again. Hydroxyprogesterone is a man-made form of a female hormone (progestin). It is not known how it works to prevent preterm births. This medication is not intended to prevent preterm birth in women pregnant with more than one baby (such as twins, triplets). It is also not intended to stop active preterm labor.


How to use HYDROXYPROGESTERONE CAPROATE - INJECTION

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start using hydroxyprogesterone and each time you get a refill. If you have any questions, ask your doctor or pharmacist. This medication is given by injection as directed by your doctor, usually once a week (every 7 days). The injection is given by a health care professional, either under the skin of your upper arm or into the muscle of your buttocks. You will start receiving injections any time from the 16th week through the 20th week of your pregnancy. You will continue to receive injections once a week until week 37 of your pregnancy or when your baby is delivered, whichever comes first. Use this medication regularly to get the most benefit from it.

Side Effects

SIDE EFFECTS: Pain, swelling, itching, bruising, or a lump at the injection site may occur. Nausea or diarrhea may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: dark urine, mental/mood changes (such as depression, nervousness), persistent nausea/vomiting, stomach/abdominal pain, unusual vaginal bleeding, yellowing eyes/skin. This drug may rarely cause blood clots. Get medical help right away if any of these serious side effects occur: chest/jaw/left arm pain, confusion, pain/swelling/redness/warmth in the leg, slurred speech, sudden shortness of breath, sudden vision changes (such as partial/complete blindness), weakness on one side of the body. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using hydroxyprogesterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, blood clots or other blood clotting problems, cancer (especially of the breast or other female organs), depression, diabetes, severe headaches/migraines, heart problems, high blood pressure, kidney problems, liver problems, seizure disorder, unusual vaginal bleeding, yellowing eyes/skin (jaundice) during pregnancy. If you have diabetes, this medication may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Tell your doctor if you will be having surgery or will be confined to a chair or bed for a long time (such as a long plane flight). You may need to take special precautions. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication is used to prevent preterm birth during pregnancy. Discuss the risks and benefits with your doctor. This drug may pass into breast milk. However, it is not used after 37 weeks of pregnancy, or after delivery. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for HYDROXYPROGESTERONE CAPROATE - INJECTION

Hydroxyprogesterone caproate is a medication that is injected into the muscle to prevent preterm birth in women who have had a previous preterm delivery.

Hydroxyprogesterone caproate works by helping to maintain pregnancy by reducing the risk of preterm birth.

Hydroxyprogesterone caproate is given as an injection into the muscle, usually in the buttocks.

Hydroxyprogesterone caproate is usually given once a week, beginning between the 16th and 20th week of pregnancy and continuing until the 37th week.

The most common side effects of hydroxyprogesterone caproate include pain at the injection site, swelling or itching at the injection site, hives, rash, and nausea.

Serious side effects of hydroxyprogesterone caproate are rare but can include blood clots, allergic reactions, and liver problems. It is important to seek medical attention if any of these occur.

There is limited information on the use of hydroxyprogesterone caproate during breastfeeding, so it is best to consult with a healthcare provider before using this medication while breastfeeding.

Hydroxyprogesterone caproate should be used with caution in women with a history of blood clots. A healthcare provider will assess the risks and benefits before prescribing this medication.

Hydroxyprogesterone caproate is typically considered safe for use in all trimesters of pregnancy. However, it should only be used under the guidance of a healthcare provider.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.