GUSELKUMAB - INJECTION
PHONETIC PRONUNCIATION: (GUE-sel-KOO-mab)
COMMON BRAND NAME(S): Tremfya
GENERIC NAME(S): guselkumab
Uses
USES: This medication is used to treat plaque psoriasis that is too severe to be treated with only products applied to the skin. Guselkumab belongs to a class of drugs known as monoclonal antibodies. It works by blocking a certain natural substance in your body (interleukin-23) that may lead to the overgrowth of skin cells and redness/swelling seen in plaque psoriasis. Guselkumab can help lessen the symptoms of plaque psoriasis, including red, scaly, itchy patches of skin.
How to use GUSELKUMAB - INJECTION
HOW TO USE: Read the Medication Guide and Instructions for Use provided by your pharmacist before you start using guselkumab and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Before treatment with this medication, your doctor will test you for tuberculosis (TB). Your doctor should also monitor you for symptoms of TB during and after treatment with this drug. If needed, treatment for tuberculosis or other infections should be given before receiving this medication. This medication is given by injection under your skin as directed by your doctor. You may receive your first dose in the doctor's office. After the first dose, another dose is usually given 4 weeks later, followed by doses every 8 weeks. The injection is given in the upper arms, thighs, or abdomen (at least 2 inches from your belly button). The dosage is based on your medical condition and response to treatment. Follow your doctor's instructions carefully. If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product instructions. Wash your hands before using this medication. Remove the medication from the refrigerator 30 minutes before you inject it to allow it to reach room temperature. Do not warm up this medication any other way such as by heating in the microwave, placing in hot water, or leaving it in direct sunlight. Do not shake the medication. The medication should be colorless to light yellow. It may contain small white or clear particles. Before using, check this product visually for cloudiness, large particles, or discoloration. If you see any of these things, do not use the liquid. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into skin that is tender, bruised, red, hard, thick, scaly, or affected by psoriasis. To lessen bruising, do not rub the injection site after a shot. Learn how to store and discard medical supplies safely. Use this medication regularly to get the most benefit from it. It may help to mark your calendar with a reminder. Tell your doctor if your condition does not get better or if it gets worse.
Side Effects
Precautions
Interactions
Overdose
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Faq for GUSELKUMAB - INJECTION
Guselkumab injection is used to treat moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.
Guselkumab is a monoclonal antibody that specifically targets and blocks a protein called interleukin-23 (IL-23). By inhibiting IL-23, Guselkumab helps to regulate an overactive immune system that contributes to psoriasis symptoms.
Guselkumab is typically given as an injection once every 8 weeks after two starter doses given 4 weeks apart.
Guselkumab is administered as a subcutaneous injection, meaning it is injected under the skin. It can be self-administered with proper training or administered by a healthcare professional.
Common side effects of Guselkumab injection include upper respiratory infections, injection site reactions, headache, and diarrhea. Serious side effects can occur and should be reported to a doctor immediately.
It is important to inform your doctor about any other medical conditions you have before starting Guselkumab. Special caution may be needed if you have a history of infections, tuberculosis, or inflammatory bowel disease.
You should inform your doctor about all the medications you are taking, including prescription and over-the-counter drugs, as well as any herbal supplements. Some medications may interact with Guselkumab and need to be adjusted or avoided.
Individual responses to Guselkumab may vary, but improvement in psoriasis symptoms is typically seen within 12 to 16 weeks of starting treatment.
While there are no specific interactions between Guselkumab and alcohol, excessive alcohol consumption can worsen psoriasis symptoms. It is generally recommended to limit alcohol intake.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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