FLUOCINOLONE/TRETINOIN/HYDROQUINONE - TOPICAL

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FLUOCINOLONE/TRETINOIN/HYDROQUINONE - TOPICAL

PHONETIC PRONUNCIATION: (FLOO-oh-SIN-oh-lone/tret-ih-NO-in/hi-dro-KWIN-own)

COMMON BRAND NAME(S): Tri-Luma

GENERIC NAME(S): fluocinolone acetonide/tretinoin/hydroquinone

Uses

USES: This combination medication is used to treat melasma on the face. Melasma is a condition of dark patchy areas on the skin, especially on the cheeks and forehead. It sometimes occurs with hormone changes. This product contains 3 different kinds of medication. Hydroquinone is a reversible skin bleaching agent. Tretinoin is a retinoid that increases skin shedding. Fluocinolone is a medium strength corticosteroid that reduces swelling, itching, and redness. This medication may improve your melasma, but it is not a cure. Continued exposure to some of the causes of melasma (e.g., sunlight, estrogen-type birth control hormones) may cause it to return.


How to use FLUOCINOLONE/TRETINOIN/HYDROQUINONE - TOPICAL

HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start using this product and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Before using, apply a small amount of this medicine to an area of unbroken skin, and check the area within 24 hours for any serious side effects. If the test area is itching, red, puffy, or blistering, do not use this product and contact your doctor. If there is just mild redness, then treatment with this product may begin. Before using, gently wash your face and neck with a mild soapless cleanser. Rinse and pat dry the skin. Apply a thin layer of medication to the affected area, including about 1/2 inch (1.5 centimeters) of normal-appearing skin around the affected area, once daily 30 minutes before bedtime or as directed by your doctor. Rub the medication into the skin gently and completely. Do not bandage, cover, or wrap the area unless directed to do so by your doctor. This medication may make the treated areas of skin more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen of SPF 30 or greater and wear protective clothing on the treated areas of skin when outdoors, even on cloudy or hazy days. If you experience dry skin from using this product, you may use a skin moisturizer in the morning after washing your face. You may also use a moisturizer and cosmetics during the day while using this medication. Avoid getting this product in your eyes or on the inside of your nose or mouth. If you do get this medication in those areas, flush with plenty of water. If severe irritation occurs, seek medical attention promptly. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each night. Since this drug is absorbed through the skin and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication. It may take up to 4 weeks to notice significant improvement. However, this medication is not recommended for long-term use (e.g., longer than 8 weeks) without stopping the medication for short periods. Inform your doctor if your condition persists or worsens after 4 weeks of treatment.

Side Effects

SIDE EFFECTS: See also How to Use. Mild burning, stinging, redness, dryness, or acne may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: blistering, skin cracking/shedding, "spider veins" (telangiectasia), stretch marks, other skin discoloration (besides melasma), "hair bumps" (folliculitis), blue-black darkening of the skin, numbness/tingling of hands/feet, increased pain/touch sensitivity. Rarely, it is possible this medication will be absorbed from the skin into the bloodstream. This can lead to side effects of too much corticosteroid. These side effects are more likely in children and people who use this medication for a long time or over large areas of the skin. Tell your doctor right away if any of the following side effects occur: unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination, vision problems. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice any other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using fluocinolone/tretinoin/hydroquinone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., hydrocortisone, prednisone); or to vitamin A-related drugs (other retinoids such as isotretinoin); or if you have any other allergies. This product may contain inactive ingredients (such as sulfites), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, open sores or broken areas of skin (especially on the face or hands), other skin conditions (e.g., eczema, psoriasis). Too much bleaching of the skin might occur in some cases, resulting in an undesirable cosmetic effect in those with darker skin. Consult your doctor or pharmacist for more details. Rarely, using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past few months. Children may be more sensitive to the effects of too much corticosteroid medication. Though it is very unlikely to occur with corticosteroids applied to the skin, this medication may temporarily slow down a child's rate of growth if used for long periods. However, it will probably not affect final adult height. Monitor your child's height periodically. This medication is not recommended for use during pregnancy. One medication in this product (tretinoin) has caused harm to an unborn baby when taken by mouth. Discuss the risks and benefits with your doctor. Since this drug is absorbed through the skin and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication. It is not known whether these drugs pass into breast milk when applied to the skin. Consult your doctor before breast-feeding. Avoid skin-to-skin contact with your infant in areas where this product has been used.

Interactions

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other medicated skin products (e.g., soaps, cleansers, skin medications, skin-drying cosmetics), hormone-based birth control products (e.g., birth control pills, hormone implants), cosmetic products or drugs that increase the skin's sensitivity to the sun (e.g., tanning products, tetracyclines, quinolones such as ciprofloxacin). This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Overdose

OVERDOSE: This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

TRI-LUMA CREAM
TRI-LUMA CREAM
TRI-LUMA CREAM
color
light yellow
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Faq for FLUOCINOLONE/TRETINOIN/HYDROQUINONE - TOPICAL

Fluocinolone/Tretinoin/Hydroquinone topical is used to treat dark spots, melasma, and other skin discolorations caused by the sun, aging, or hormonal changes.

Fluocinolone is a steroid that reduces inflammation and redness. Tretinoin is a derivative of vitamin A that helps to exfoliate the skin and promote the growth of new, healthier skin cells. Hydroquinone is a skin-lightening agent that works by inhibiting the production of melanin, the pigment responsible for dark spots.

Apply a thin layer of the medication to the affected area once daily, usually at bedtime. Avoid applying the medication to broken or irritated skin, as well as the mouth, eyes, or inside the nose. Wash your hands after applying the medication.

Results may vary, but noticeable improvement in skin discoloration is usually seen within 4 to 6 weeks of regular use. However, it may take several months of continued use to achieve the full effect.

Common side effects include mild irritation, dryness, redness, or peeling of the skin. These side effects are usually temporary and may resolve with continued use. However, if you experience severe or persistent irritation, rash, or allergic reactions, consult your doctor immediately.

It is important to consult your doctor before using this medication during pregnancy or while breastfeeding. While no conclusive evidence suggests harm to unborn babies or nursing infants, caution is advised.

Apply a thin layer of the medication to the affected area(s) once daily, usually in the evening. Make sure to wash and dry the skin thoroughly before applying the medication.

The results may vary for each individual, but improvement in skin condition can be observed within a few weeks of regular use. However, it may take several months for complete improvement.

Common side effects may include redness, peeling, dryness, and itching of the skin. Serious side effects are rare but could include severe skin irritation or allergic reactions. Consult your doctor if you experience any unusual or severe side effects.

It is advisable to avoid using other irritating or drying skincare products, such as harsh soaps or cleansers, while using this medication. Additionally, it is important to protect the treated area from excessive sun exposure and to use sunscreen regularly.

The duration of use may vary depending on the severity of the condition and individual response. It is best to follow your doctor's instructions regarding the duration of treatment.

Avoid applying this medication to sensitive areas or mucous membranes like the lips or near the eyes unless specifically instructed by your doctor. It is vital to follow the recommended application guidelines to prevent any unwanted effects.

If you forget to apply the medication as scheduled, apply it as soon as you remember. However, if it is close to the time for the next dose, skip the missed dose and continue with your regular application schedule.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.