FACTOR IX, RECOMBINANT - INJECTION

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FACTOR IX, RECOMBINANT - INJECTION

PHONETIC PRONUNCIATION: (FACK-ter nine)

COMMON BRAND NAME(S): Alprolix, Benefix, Ixinity

GENERIC NAME(S): factor IX human recombinant

Uses

USES: This medication is used to prevent or control bleeding in people with little or no factor IX (due to hemophilia B, Christmas disease). Factor IX is a protein (clotting factor) in the blood that works with other clotting factors to help the blood clot and therefore stop bleeding. People with little or no factor IX are at risk for bleeding longer after an injury/surgery or bleeding suddenly (often in the joints/muscle) without an obvious cause. This medication should not be used to treat other types of factor deficiencies (e.g., factors II, VII, VIII, X) or factor problems (e.g., inhibitor to factor XIII), to reverse the effects of "blood thinners" (e.g., warfarin), or to treat bleeding from low levels of liver-dependent clotting factors (due to liver problems).


How to use FACTOR IX, RECOMBINANT - INJECTION

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start using factor IX and each time you get a refill. If you have any questions, ask your doctor or pharmacist. This medication is given by injection into a vein over several minutes as directed by your doctor. Dosage is based on your medical condition (e.g., amount and location of bleeding), weight, and response to treatment. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. The medication in the vial and the supplies that come with the medication should be used only once. Do not reuse. For some brands, it is important to limit the amount of blood entering the tubing and to avoid letting any blood enter the syringe. You may need to use a new vial of medication and new set of supplies if this occurs. Consult your pharmacist for details. Tell your doctor if your condition persists or worsens.

Side Effects

SIDE EFFECTS: Fever, pain at injection site, chills, headache, flushing, weakness, nausea, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: swelling at injection site, shortness of breath, fast heartbeat, signs of kidney problems (such as change in the amount of urine), swelling of the ankles/feet, pain/redness/swelling of arms or legs, new or increased bleeding/bruising. Get medical help right away if any of these rare but very serious side effects occur: bluish fingers, chest pain, trouble breathing. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using factor IX, tell your doctor or pharmacist if you are allergic to factor IX products; or to hamster protein; or if you have any other allergies. This product may contain inactive ingredients (such as latex), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: other clotting disorders (e.g., disseminated intravascular coagulation-DIC), recent surgery/procedure, liver disease. Before having surgery, tell your doctor or dentist that you are using this medication. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: drugs that help with clotting (such as aminocaproic acid, tranexamic acid).

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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IXINITY 2,000 UNIT RANGE
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IXINITY 3,000 UNIT RANGE
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IXINITY 1,000 UNIT RANGE-2 VLS
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IXINITY 250 UNIT RANGE
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IXINITY 2,000 UNIT RANGE
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Faq for FACTOR IX, RECOMBINANT - INJECTION

Factor IX, Recombinant is a medication used to replace clotting factor IX in patients with hemophilia B, a bleeding disorder. It helps prevent or control bleeding episodes in these patients.

Factor IX, Recombinant is administered through injection into a vein. It is usually given by a healthcare professional, but some patients can learn to self-administer under proper guidance.

The common side effects of Factor IX, Recombinant may include headache, dizziness, nausea, vomiting, fatigue, injection site reactions, and allergic reactions. It is important to notify your healthcare provider if you experience any unusual or severe side effects.

The dosage and frequency of Factor IX, Recombinant administration vary depending on the individual patient's needs and the severity of their condition. Your healthcare provider will determine the appropriate schedule for you.

Yes, Factor IX, Recombinant can be used in children with hemophilia B. The dosage and administration guidelines may differ for pediatric patients, so it is important to follow your healthcare provider's instructions.

Factor IX, Recombinant should not be used in individuals who are allergic to it or have a known hypersensitivity to hamster proteins. It is important to inform your healthcare provider about any other medical conditions or medications you are taking before starting treatment.

Factor IX, Recombinant should be stored in the refrigerator at recommended temperatures. It should not be frozen, and the solution should be clear or slightly opalescent before use. Always check the expiration date and discard any expired medication.

If you miss a dose of Factor IX, Recombinant, contact your healthcare provider for instructions. It is important to follow the prescribed dosing schedule to maintain effective clotting factor levels.

Before undergoing any surgical or dental procedures, it is important to inform your healthcare provider about your use of Factor IX, Recombinant. Adjustments to your medication or additional preventive measures may be necessary to minimize bleeding risks.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.