FACTOR IX, HUMAN - INJECTION

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FACTOR IX, HUMAN - INJECTION

PHONETIC PRONUNCIATION: (FACK-ter nine)

COMMON BRAND NAME(S): Alphanine SD, Konyne, Proplex T

GENERIC NAME(S): factor IX complex, prothrombin cplx conc(pcc) no.4, 3-factor

Uses

USES: This medication is used to prevent or control bleeding in people with little or no factor IX (due to hemophilia B, Christmas disease). Factor IX is a protein (clotting factor) in the blood that works with other clotting factors to help the blood clot and therefore stop bleeding. People with little or no factor IX are at risk for bleeding longer after an injury/surgery or bleeding suddenly (often in the joints/muscle) without an obvious cause. This medication should not be used to reverse the effects of "blood thinners" (e.g., warfarin). Most types of this medication should not be used to treat other types of factor deficiencies (e.g., factors II, VII, VIII, X) or factor problems (e.g., inhibitor to factor XIII). If you are using this medication for one of these conditions, consult your doctor or pharmacist to make sure that you are using the right product.


How to use FACTOR IX, HUMAN - INJECTION

HOW TO USE: This medication is given by injection into a vein as directed by your doctor. Dosage is based on your medical condition (e.g., amount and location of bleeding), weight, and response to treatment. Gently swirl the medication to mix. Do not shake. Some forms of this medication must be completely mixed into the liquid so that the liquid contains no particles. In these cases, do not use the liquid if it contains particles. Other forms of this medication may occasionally contain a few small particles in the vial, even if the medication is mixed correctly. In these cases, the particles will not affect how well the medication works and will be removed by the filter. If you have questions about whether your form of this medication may be used if it contains particles, or if you have other questions about the use of this medication, consult the doctor or pharmacist. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Learn how to store and discard medical supplies safely. The medication in the vial and the supplies that come with the medication should be used only once. Do not reuse. Tell your doctor if your condition persists or worsens.

Side Effects

SIDE EFFECTS: Pain at injection site, chills, tingling, flushing, headache, nausea, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: swelling at injection site, fast heartbeat, shortness of breath, signs of kidney problems (such as change in the amount of urine), swelling of the ankles/feet, pain/redness/swelling of arms or legs, new or increased bleeding/bruising. Get medical help right away if any of these rare but very serious side effects occur: chest pain, trouble breathing, bluish fingers. This medication is made from human blood. Even though donors are carefully screened and this medication goes through a special manufacturing process, there is a very small chance that you may get infections from the medication (e.g., viral infections such as hepatitis). Tell your doctor right away if you develop any signs of hepatitis/another infection, including fever, persistent sore throat, unusual tiredness, persistent nausea/vomiting, yellowing eyes/skin, dark urine. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using factor IX, tell your doctor or pharmacist if you are allergic to factor IX products; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: other clotting disorders (e.g., disseminated intravascular coagulation-DIC), heart disease (e.g., coronary artery disease), immune system problems, recent surgery/procedure, liver disease. Before having surgery, tell your doctor or dentist that you are using this medication. Since this medication is made from human blood, there is a very small chance that you may get infections from it (e.g., viral infections such as hepatitis). It is recommended that you get the appropriate vaccinations (e.g., for hepatitis A and B) and that people giving this medication handle the medication with special caution to prevent viral infections. Consult your doctor for more details. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: drugs that help with clotting (such as aminocaproic acid, tranexamic acid).

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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Faq for FACTOR IX, HUMAN - INJECTION

Factor IX, Human - Injection is used to prevent and control bleeding episodes in individuals with hemophilia B, a genetic disorder that affects the blood's ability to clot.

Factor IX, Human - Injection replaces the deficient or defective Factor IX protein in individuals with hemophilia B. This allows the blood to clot normally and prevents spontaneous bleeding episodes.

Common side effects of Factor IX, Human - Injection may include allergic reactions, dizziness, headache, flushing, nausea, and injection site reactions such as redness, itching, or swelling.

Factor IX, Human - Injection is administered intravenously (into a vein) by a healthcare professional. The dosage and frequency of administration may vary depending on the individual's condition and response to treatment.

In some cases, individuals with hemophilia B can be trained to self-administer Factor IX, Human - Injection. However, this should only be done under the guidance and supervision of a healthcare professional.

The effect of Factor IX, Human - Injection varies among individuals but usually lasts for around 12 to 24 hours. The frequency of administration is determined by the individual's bleeding pattern, severity of the condition, and factors such as surgery or injury.

Factor IX, Human - Injection should be used with caution in individuals with known allergies to any components of the medication. It should also be used with caution in individuals who have experienced hypersensitivity reactions to other similar products.

The use of Factor IX, Human - Injection during pregnancy or breastfeeding should be discussed with a healthcare professional. The potential benefits to the mother and the risks to the fetus or infant should be carefully evaluated.

There are no reported significant drug interactions with Factor IX, Human - Injection. However, it is important to inform your healthcare professional about all medications, including over-the-counter drugs, vitamins, and herbal supplements, that you are currently taking.

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Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.