ESTRADIOL INSERT - VAGINAL
PHONETIC PRONUNCIATION: (ES-tra-DYE-ol)
COMMON BRAND NAME(S): Imvexxy
GENERIC NAME(S): estradiol
Uses
USES: This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.
How to use ESTRADIOL INSERT - VAGINAL
HOW TO USE: Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Wash and dry your hands before handling the insert. Select the best position for vaginal insertion that is most comfortable for you. Hold the insert with the larger end between your fingers and place it about 2 inches into your vagina as directed. Use this medication vaginally as directed by your doctor, usually once daily for the first 2 weeks, then 2 times a week, every 3 to 4 days (for example, every Monday and Thursday). The dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, mark the days on your calendar when you will be using this medication. Do not increase your dose or use this medication more often or for longer than prescribed. Tell your doctor if your condition does not get better or if it gets worse.
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Warning
WARNING: Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia. Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding. In postmenopausal women, estrogens can increase the risk of cancer of the ovaries, stroke, dementia, and serious blood clots in the legs. Estrogens alone do not appear to increase the risk of breast cancer when used for up to 7 years. Estrogen, when used with a progestin, can increase the risk of heart disease (such as heart attacks), stroke, serious blood clots in the lungs/legs, dementia, and cancer of the breast/ovaries. The risk for serious side effects may depend on the dose of estrogen and the length of time it is used. Therefore, this medication should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of this medication with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to use this medication. If you will be using this medication long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor. See also Notes section.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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