EDOXABAN - ORAL

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EDOXABAN - ORAL

PHONETIC PRONUNCIATION: (e-DOX-a-ban)

COMMON BRAND NAME(S): Savaysa

GENERIC NAME(S): edoxaban tosylate

Uses

USES: Edoxaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation). It is also used to treat certain blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE). Edoxaban is an anticoagulant that works by blocking certain clotting proteins in your blood.


How to use EDOXABAN - ORAL

HOW TO USE: See also Warning section. Read the Medication Guide provided by your pharmacist before you start taking edoxaban and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition, weight, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). If you have trouble swallowing the tablet whole, you may crush the tablet and mix it with 2 to 3 ounces (60 to 90 milliliters) of water or applesauce. Drink or eat the entire mixture right away. Do not prepare a supply for future use. If you are giving this medication through a tube into the stomach (gastric tube), ask your health care professional for detailed instructions on how to properly mix and give it. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Side Effects

SIDE EFFECTS: See also Warning section. Easy bruising or minor bleeding (such as nosebleed, bleeding from cuts) may occur. If either of these effects persists or worsens, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication can cause serious bleeding if it affects your blood clotting proteins too much. Tell your doctor right away if you have any signs of serious bleeding, including: unusual pain/swelling/discomfort, unusual bruising, prolonged bleeding from cuts or gums, persistent/frequent nosebleeds, unusually heavy/prolonged menstrual flow, pink/dark urine, coughing up blood, vomit that is bloody or looks like coffee grounds, severe headache, dizziness/fainting, unusual or persistent tiredness/weakness, bloody/black/tarry stools, difficulty swallowing. Get medical help right away if you have any signs of very serious bleeding, including: vision changes, confusion, slurred speech, weakness on one side of the body. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking edoxaban, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, bleeding problems (such as bleeding of the stomach/intestines, bleeding in the brain), blood disorders (such as anemia, hemophilia, thrombocytopenia), recent major injury/surgery, frequent falls/injuries, stroke. Before having surgery or any medical/dental procedures (especially spinal puncture or spinal/epidural anesthesia), tell your doctor or dentist that you are taking this medication and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor or dentist may tell you to stop taking edoxaban before your surgery. Ask for specific instructions about stopping or starting this medication. This medication may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages. Ask your doctor or pharmacist about how much alcohol you may safely drink. This medication can cause bleeding. To lower the chance of getting cut, bruised, or injured, use great caution with sharp objects like safety razors and nail cutters. Use an electric razor when shaving and a soft toothbrush when brushing your teeth. Avoid activities such as contact sports. If you fall or injure yourself, especially if you hit your head, contact your doctor right away. Your doctor may need to check you for hidden bleeding that could be serious. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor before using this medication. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: mifepristone, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin, enoxaparin), certain antidepressants (including SSRIs such as fluoxetine, SNRIs such as desvenlafaxine/venlafaxine). Other medications can affect the removal of edoxaban from your body, which may affect how edoxaban works. One example is rifampin, among others. Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as ibuprofen or naproxen) that may increase your risk for bleeding if taken together with this medication. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: bloody/black/tarry stools, pink/dark urine, unusual/prolonged bleeding.

Images

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Faq for EDOXABAN - ORAL

Edoxaban is an oral medication used for the prevention and treatment of blood clots. It belongs to a class of drugs known as factor Xa inhibitors.

Edoxaban is primarily used to prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients who have had knee or hip replacement surgery. It is also prescribed to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

Edoxaban works by inhibiting the action of factor Xa, a crucial enzyme that is involved in the blood clotting process. By blocking factor Xa, Edoxaban helps to prevent the formation of blood clots and reduces the risk of thrombotic events.

The common side effects of Edoxaban include bleeding, bruising, nausea, vomiting, stomach pain, and itching. It is important to report any unusual or severe side effects to your healthcare provider.

Edoxaban is usually taken once daily with or without food. It is important to follow the prescribed dosage and schedule provided by your doctor. Do not stop taking Edoxaban without consulting your healthcare provider.

Yes, there are several medications and substances that can interact with Edoxaban, including other anticoagulants, antiplatelet drugs, certain antibiotics, and herbal supplements. It is essential to inform your doctor about all the medications you are taking to avoid potential drug interactions.

Edoxaban is not recommended for use during pregnancy, as it may harm the unborn baby. It is also not known whether Edoxaban passes into breast milk. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Edoxaban.

If you miss a dose of Edoxaban, take it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

While there are no specific dietary restrictions while taking Edoxaban, it is important to maintain a balanced diet and avoid excessive intake of foods that have blood-thinning properties, such as ginger, garlic, and green tea. Consult your doctor or pharmacist for further guidance.

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Warning

WARNING: Your doctor should order a blood test to check your kidney function before starting you on edoxaban. In people whose kidneys work really well, this medication may not be effective in preventing blood clots due to atrial fibrillation. Therefore, this medication is not recommended for use by these people for this purpose. Talk to your doctor for more details. Do not stop taking edoxaban unless directed by your doctor. If you stop taking this medication early, you have a higher risk of forming a serious blood clot (such as a stroke, blood clot in the legs/lungs). Your doctor may direct you to take a different "blood thinning" or antiplatelet medication to reduce your risk. Get medical help right away if you have weakness on one side of the body, trouble speaking, sudden vision changes, confusion, chest pain, trouble breathing, pain/warmth/swelling in the legs. People taking this medication may bleed near the spinal cord after certain spinal procedures. Bleeding in this area can cause paralysis that lasts a long time or could become permanent. Ask your doctor about the benefits and risks before any spinal procedure. The risk of bleeding may be higher if you have a deformed spine, or have had spinal procedures/surgery before (such as epidural catheter placement, difficult epidural/spinal puncture), or are taking other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin/enoxaparin, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen). Tell your doctor right away if you notice symptoms such as back pain, leg numbness/tingling/weakness, loss of control of the bowels or bladder (incontinence).


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.