ECALLANTIDE - INJECTION

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ECALLANTIDE - INJECTION

PHONETIC PRONUNCIATION: (e-KAL-lan-tide)

COMMON BRAND NAME(S): Kalbitor

GENERIC NAME(S): ecallantide

Uses

USES: This medication is used to treat an acute attack of a certain immune disease passed down through families (hereditary angioedema-HAE). Ecallantide blocks a natural substance produced by the body (kallikrein) which acts to increase amounts of another natural substance (bradykinin) thought to cause the symptoms seen during an acute attack of HAE. This medication does not cure HAE. Ecallantide may lessen the symptoms during an acute attack of HAE such as rapid swelling and pain of the hands, feet, limbs, face, tongue, or throat. When attacks involve the intestines, symptoms may include abdominal pain/cramps, diarrhea or vomiting. Attacks of swelling may occur without reason. However, anxiety, stress, sickness, and surgery may trigger attacks in some people.


How to use ECALLANTIDE - INJECTION

HOW TO USE: Read the Medication Guide provided by your pharmacist before you start using ecallantide and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Your healthcare provider will inject this medication under your skin either in the abdomen, thigh, or upper arms as directed by your doctor. You will receive three separate shots which should be separated by at least 2 inches (5 centimeters). An additional three shots may be given in a 24-hour period if the HAE attack continues. Do not receive an injection into skin that is tender, red, or hard. Dosage is based on your medical condition and response to treatment. Tell your doctor if your condition does not improve or if it worsens.

Side Effects

SIDE EFFECTS: See also Warning section. Bruising, itching, redness, swelling of the skin at the injection site may occur. Nausea, fever, or stuffy nose may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using ecallantide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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KALBITOR 10 MG/ML VIAL
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Faq for ECALLANTIDE - INJECTION

Ecallantide is an injection medication used to treat hereditary angioedema (HAE), a rare genetic condition that causes swelling in various body parts.

Ecallantide works by blocking the activity of a protein called kallikrein, which is responsible for causing swelling in HAE patients.

Ecallantide is administrated via subcutaneous (under the skin) injection. It is usually given by a healthcare professional, but some patients may be trained to self-administer the injections.

Common side effects of Ecallantide may include injection site reactions (such as pain, swelling, or redness), headache, diarrhea, nausea, and fever. However, not everyone experiences these side effects.

The dosing frequency of Ecallantide may vary depending on the individual patient's HAE symptoms. Your healthcare provider will determine the appropriate dosing schedule for you.

Ecallantide is not approved for use in children under the age of 12. However, it may be prescribed off-label for certain pediatric patients under the guidance of a healthcare provider.

Ecallantide should not be used in patients who have a known allergy or hypersensitivity to the medication. It is important to inform your healthcare provider about any other medications or medical conditions you have before starting Ecallantide.

Clinical trials have shown that Ecallantide can effectively reduce the frequency and severity of HAE attacks. However, individual results may vary, and it may not eliminate all symptoms.

Ecallantide starts working within hours of administration, with peak effects typically observed within 1-3 hours. However, the duration of response can vary among patients.

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Warning

WARNING: Ecallantide may rarely cause serious (rarely fatal) allergic reactions. Patients who experience a severe allergic reaction with this drug must never use it again. Because the symptoms can be the same for an allergic reaction and the condition which this medication treats, you will be monitored closely by your healthcare providers as you receive this medication in a clinic or hospital. Immediate medical attention should be provided if you develop any signs of an allergic reaction such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, or chest pain.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.