DROSPIRENONE/ESTRADIOL - ORAL
PHONETIC PRONUNCIATION: (droh-SPYE-re-none/ess-truh-DYE-all)
COMMON BRAND NAME(S): Angeliq
GENERIC NAME(S): drospirenone/estradiol
Uses
USES: This medication is used to reduce menopause symptoms. It helps reduce episodes of flushing and sweating of the upper body and face, commonly called hot flashes. It also helps treat dryness, itching, and burning around the vagina. These symptoms occur when a woman's body no longer makes the usual amount of female hormone (estrogen). This medication is a combination of 2 types of female hormones: an estrogen (estradiol) and a progestin (drospirenone). A progestin is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. A woman who has had her uterus removed does not need progestin and should not be treated with this combination medication. If you need treatment only for vaginal menopause symptoms, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected.
How to use DROSPIRENONE/ESTRADIOL - ORAL
HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth, usually once daily or as directed by your doctor. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Inform your doctor if your condition does not improve or if it worsens.
Side Effects
Precautions
Interactions
Overdose
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Faq for DROSPIRENONE/ESTRADIOL - ORAL
Drospirenone/estradiol oral medication is used as a combined hormone replacement therapy (HRT) to relieve menopause symptoms in women, such as hot flashes, vaginal dryness, and night sweats.
Drospirenone and estradiol are the active ingredients in this medication. Drospirenone is a synthetic progestin that works by helping to regulate the menstrual cycle and prevent the overgrowth of the lining of the uterus. Estradiol is a natural estrogen hormone that helps alleviate menopause symptoms by supplementing the body's hormone levels.
It is typically taken once daily with or without food, preferably at the same time each day. Follow the instructions provided by your healthcare provider or the prescription label for the correct dosage.
Common side effects may include headache, breast pain, nausea, bloating, or changes in weight. However, if you experience more serious side effects like mood changes, severe abdominal pain, chest pain, or unusual vaginal bleeding, seek immediate medical attention.
Certain medications, including aromatase inhibitors, tamoxifen, and St. John's wort, may interact with drospirenone/estradiol and reduce its effectiveness or increase the risk of side effects. It is important to inform your doctor about all the medications or supplements you are taking before starting this medication.
No, drospirenone/estradiol oral medication is not intended to be used as a contraceptive method or birth control. It is specifically approved and prescribed for menopause symptom relief and not for preventing pregnancy.
The duration of treatment varies depending on individual needs and health considerations. It is best to consult with your healthcare provider to determine the appropriate length of treatment for your specific situation.
If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
No, drospirenone/estradiol oral medication is specifically approved for use in postmenopausal women and should not be used by men.
Warning
WARNING: Rarely, very serious side effects have occurred when estrogen-only and combination hormone replacement therapies (estrogen and progestin HRT) are used after menopause. Discuss the risks and benefits of hormone treatment and your personal health history with your doctor. Combination HRT should not be used to prevent heart disease or dementia. Combination HRT can rarely cause heart disease (e.g., heart attacks), stroke, serious blood clots (pulmonary embolism and deep venous thrombosis), dementia, and breast cancer. The risk for stroke and breast cancer increases with age, especially for women older than 75. Estrogens may also increase the risk of cancer of the ovaries. Some of these risks appear to depend on the length of time this drug is used and the amount of estrogen per dose. Therefore, this medication should be used for the shortest possible length of time at the lowest effective dose, so you can obtain the benefits and minimize the chance of serious side effects from long-term treatment. Discuss the details with your doctor and check with him/her regularly (e.g., every 3-6 months) to see if you still need to take this medication. If you use this drug for an extended time, you should have a complete physical exam at regular intervals (e.g., once a year) or as directed by your doctor. See Notes section.
Disclaimer
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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