DACLATASVIR - ORAL

DACLATASVIR - ORAL

PHONETIC PRONUNCIATION: (dak-LAT-as-vir)

COMMON BRAND NAME(S): Daklinza

GENERIC NAME(S): daclatasvir dihydrochloride

Uses

USES: Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Daclatasvir should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. It is not known if this treatment can prevent you from passing the virus to others. Do not share needles, and practice "safer sex" (including the use of latex condoms) to lower the risk of passing the virus to others.


How to use DACLATASVIR - ORAL

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking daclatasvir and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Also read the drug information for your other antiviral medication(s). Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication works best when the amount of drug in your body is kept at a constant level. Take this drug at evenly spaced intervals. To help you remember, take it at the same time each day. Continue to take daclatasvir and your other antiviral medication(s) for the full length of time prescribed, even if your symptoms disappear after a short time. Stopping any of the drugs too early may result in a return of the infection.

Side Effects

SIDE EFFECTS: See also Warning section. Tiredness, headache, nausea, or diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking daclatasvir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, other liver problems (such as hepatitis B). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, daclatasvir should be used only when clearly needed. Discuss the risks and benefits with your doctor. Daclatasvir, in combination with ribavirin, must not be used during pregnancy by either the pregnant woman or her male partner. The combination may harm an unborn baby. Two reliable forms of birth control (such as condoms, birth control pills) must be used whenever at least one sexual partner is using these medicines together, and for six months after stopping treatment. If you or your partner becomes pregnant, or if you think you or your partner may be pregnant, tell your doctor right away. It is unknown if daclatasvir passes into breast milk. Consult your doctor before breast-feeding. Breast-feeding is not recommended if daclatasvir is used in combination with ribavirin.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Amiodarone may interact with sofosbuvir. Tell your doctor and pharmacist if you are taking amiodarone. Other medications can affect the removal of daclatasvir from your body, which may affect how daclatasvir works. Examples include apalutamide, mitotane, rifampin, St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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DAKLINZA 30 MG TABLET

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DAKLINZA 60 MG TABLET

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Faq for DACLATASVIR - ORAL

Daclatasvir is an antiviral medication that is used in combination with other drugs to treat chronic hepatitis C. It belongs to a class of drugs called direct-acting antivirals (DAAs) and is taken orally.

Daclatasvir works by inhibiting the replication of the hepatitis C virus (HCV) in the body. It targets a specific protein called NS5A, which is essential for the virus to reproduce. By blocking this protein, Daclatasvir helps to reduce the amount of HCV in the body and may lead to a cure in some patients.

Common side effects of Daclatasvir include headache, fatigue, nausea, diarrhea, and abnormal liver function tests. These side effects are usually mild and resolve on their own. However, if they persist or become severe, it is important to inform your healthcare provider.

The duration of Daclatasvir treatment depends on various factors, such as the genotype of the hepatitis C virus and the presence of liver cirrhosis. Typically, treatment lasts for 12 to 24 weeks. Your healthcare provider will determine the appropriate duration for your specific condition.

Yes, Daclatasvir, when used in combination with other antiviral medications, has the potential to cure hepatitis C. The success rate of treatment with Daclatasvir varies depending on factors such as the genotype of the virus and the presence of liver cirrhosis. It is important to follow your prescribed treatment regimen and consult with your healthcare provider for the best chances of achieving a cure.

Daclatasvir is generally safe and effective in patients with liver cirrhosis. However, the dosage and duration of treatment may need to be adjusted based on individual patient factors and liver function tests. It is important to discuss your medical history and condition with your healthcare provider before starting Daclatasvir.

Daclatasvir may interact with certain medications, including some HIV medications, antifungal drugs, and certain cardiovascular medications. It is crucial to inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal supplements, to check for potential drug interactions.

Daclatasvir is usually taken once daily with or without food. It is important to take the medication exactly as prescribed by your healthcare provider and complete the full course of treatment. Do not skip doses or stop taking Daclatasvir without consulting your healthcare provider.

Daclatasvir may harm an unborn baby and is not recommended during pregnancy. It is also not known if Daclatasvir passes into breast milk. Therefore, it is advisable to discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before starting Daclatasvir.


Warning

WARNING: Although this medication helps many people with hepatitis C, it may cause people who also have another liver problem called hepatitis B to get worse. Before starting this medication, tell your doctor if you have ever had hepatitis B. Tell your doctor right away if you have new or worsening symptoms of liver disease, such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, dark urine or yellowing eyes/skin.


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.