COLLAGENASE OINTMENT - TOPICAL

COLLAGENASE OINTMENT - TOPICAL

PHONETIC PRONUNCIATION: (coal-ADGE-ih-naze)

COMMON BRAND NAME(S): Santyl

GENERIC NAME(S): collagenase Clostridium histolyticum

Uses

USES: This product is used to help the healing of burns and skin ulcers. Collagenase is an enzyme. It works by helping to break up and remove dead skin and tissue. This effect may also help antibiotics to work better and speed up your body's natural healing process.


How to use COLLAGENASE OINTMENT - TOPICAL

HOW TO USE: This medication is for use on the skin only. It is usually applied once daily or as directed by your doctor. If the dressing becomes soiled, collagenase may be applied more frequently. To apply, wash hands first. Clean the area as directed by your doctor. Cleaning solutions such as hydrogen peroxide, normal saline, or Dakin's solution may be used. If your doctor has directed you to use an antibiotic powder, apply it first before applying this medication. Use a wooden spatula or a gauze pad to carefully apply the collagenase ointment directly to the affected area. Bandage securely. If you are unclear about how to clean the affected area or apply this medication, consult your doctor. Avoid applying near the eyes. Be careful to apply the ointment only within the affected area. Wash hands thoroughly after applying the ointment.

Side Effects

SIDE EFFECTS: Pain or a burning feeling at the affected area may occur. Temporary redness/irritation may also occur in the skin around the affected area. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To avoid redness/irritation in the surrounding skin, be careful to apply the ointment only within the affected area. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Treatment of burns and skin ulcers by breaking up and removing dead skin and tissue may rarely increase the risk for serious infection (sepsis). Tell your doctor right away if you notice any symptoms of serious infection, including: fever/chills, fast breathing (hyperventilation), fast heartbeat, warm skin, weakness. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using collagenase, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history. Avoid using solutions that contain acid or metal as soaking liquids because these will decrease the effect of collagenase ointment (see also Drug Interactions section). It is not known whether this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: antiseptic skin products (especially those containing heavy metals such as lead, mercury, silver). Skin products containing heavy metals may decrease the effect of collagenase. If the affected area has been exposed to one of these products, wash the area well with normal saline solution before applying this ointment. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Overdose

OVERDOSE: This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

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SANTYL OINTMENT

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SANTYL OINTMENT

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Faq for COLLAGENASE OINTMENT - TOPICAL

Collagenase ointment is a topical medication that contains collagenase enzymes. These enzymes help break down and remove dead tissue and promote healing in wounds and burns.

Collagenase ointment works by breaking down the collagen present in dead tissue, allowing the body's natural healing process to take place. It helps remove non-living tissue and promote the growth of healthy tissue.

Collagenase ointment is commonly used for debriding chronic wounds, such as diabetic ulcers, pressure ulcers, and venous ulcers. It may also be used in the treatment of burns, surgical wounds, and traumatic wounds.

First, clean the wound or affected area with a mild antiseptic and pat it dry. Then, apply a thin layer of collagenase ointment directly to the wound. Cover the area with a sterile gauze dressing and secure it in place. The ointment is usually applied once a day or as directed by a healthcare provider.

Some common side effects of collagenase ointment may include skin irritation, mild redness, and pain at the application site. If any severe side effects or allergic reactions occur, such as rash, swelling, or difficulty breathing, seek medical attention immediately.

Yes, collagenase ointment is specifically designed for use on open wounds. It helps remove dead tissue and promote healing in non-healing wounds.

There is limited information available about the use of collagenase ointment in pregnant or breastfeeding women. It is recommended to consult with a healthcare provider before using it in such situations.

The safety and effectiveness of collagenase ointment in children have not been established. It is best to consult a healthcare provider for guidance on its use in pediatric patients.

The time it takes for collagenase ointment to work depends on the severity of the wound and individual factors. Improvement in wound healing may be seen within a few weeks of regular use.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.