CEVIMELINE - ORAL

CEVIMELINE - ORAL

PHONETIC PRONUNCIATION: (seh-VIMM-eh-leen)

COMMON BRAND NAME(S): Evoxac

GENERIC NAME(S): cevimeline HCl

Uses

USES: This medication is used to treat symptoms of dry mouth due to a certain immune disease (Sjogren's syndrome). Cevimeline belongs to a class of drugs known as cholinergic agonists. It works by stimulating certain nerves to increase the amount of saliva you produce, making it easier and more comfortable to speak and swallow.


How to use CEVIMELINE - ORAL

HOW TO USE: Take this medication by mouth with or without food, usually 3 times daily or as directed by your doctor. Dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. You may continue to drink water or use saliva substitutes as needed for moisture in your mouth. You may start to feel some benefit in 1 to 2 weeks. However, it may take up to 6 weeks to feel the full benefit. Tell your doctor if your condition persists or worsens.

Side Effects

SIDE EFFECTS: See also Precautions. Sweating, nausea, runny nose, flushing, frequent urge to urinate, dizziness, weakness, diarrhea, and blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. This medication may cause an increase in tears. This can be helpful if you have dry eyes. Tell your doctor if runny eyes become a problem. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: slow/fast/irregular heartbeat, shakiness (tremor), fainting, lung problems (such as increased wheezing/cough/phlegm), mental/mood changes (such as confusion, agitation), severe stomach/abdominal pain. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking cevimeline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, chronic bronchitis, chronic obstructive pulmonary disease-COPD), certain eye conditions (such as night blindness, acute iritis, narrow-angle glaucoma), heart disease (such as chest pain, heart failure, heart attack, slow heartbeat), low or high blood pressure, liver problems, gallbladder disease (such as gallstones), kidney stones, mental/mood disorders (such as depression, psychoses, thinking/understanding problems like dementia, Alzheimer's), stomach problems (such as chronic heartburn, ulcer). This drug may make you dizzy or cause vision problems, especially at night. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness or clear vision, especially at night, until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana. If cevimeline makes you sweat heavily, drink plenty of fluids so that you do not become dehydrated. If you are unable to drink enough fluids, talk with your doctor right away. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Discuss the risks and benefits with your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring. To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval. Some products that may interact with this drug include: beta blockers (such as metoprolol, atenolol). Other medications can affect the removal of cevimeline from your body, which may affect how cevimeline works. Examples include cimetidine, amiodarone, ritonavir, fluoxetine, among others. Cevimeline may cause drugs with "drying" effects (some antihistamines, anticholinergics such as certain drugs for asthma, over-active bladder, and Parkinson's) to work less well. Examples of affected drugs include chlorpheniramine, diphenhydramine, atropine, belladonna alkaloids, benztropine, ipratropium, and tolterodine. These medications can also worsen dry mouth, causing cevimeline to work less well. Consult your doctor or pharmacist for more information. Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients that could have a drying effect. Ask your pharmacist for more details. This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: extreme sweating, shakiness, slowed/irregular heartbeat, severe breathing problems, confusion, fainting, stomach/abdominal cramping.

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CEVIMELINE HCL 30 MG CAPSULE

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EVOXAC, 30mg
EVOXAC 30 MG CAPSULE

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EVOXAC, 30mg
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EVOXAC, 30mg

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Faq for CEVIMELINE - ORAL

Cevimeline is an oral medication that is used to treat symptoms of dry mouth in patients with Sjögren's syndrome, a condition that affects the salivary glands and causes dryness in the mouth and eyes.

Cevimeline works by stimulating certain receptors in the salivary glands, which increases the production of saliva, relieving the symptoms of dry mouth.

Cevimeline is usually taken three times a day, with or without food. It is important to follow the prescribed dosage and frequency as instructed by your doctor.

Common side effects of Cevimeline may include sweating, increased urination, nausea, diarrhea, stomach pain, and blurred vision. If these side effects become severe or persistent, it is important to inform your doctor.

Cevimeline may interact with certain medications, such as anticholinergic drugs, which can reduce the effectiveness of the medication. It is important to inform your doctor about all the medications you are currently taking to avoid any potential interactions.

Cevimeline may start working within a few days to a few weeks of starting the medication. However, the full effects may take several weeks to be noticeable.

It is generally recommended to avoid alcohol while taking Cevimeline as it can increase the risk of side effects such as dizziness and drowsiness.

The safety of Cevimeline during pregnancy and breastfeeding has not been adequately studied. It is important to consult with your doctor before taking Cevimeline if you are pregnant or breastfeeding.

If you miss a dose of Cevimeline, take it as soon as you remember. However, if it is already time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.



Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.