C1-ESTERASE INHIBITOR (TREATMENT), RECOMBINANT - INJECTION

  • Home
  • C1-ESTERASE INHIBITOR (TREATMENT), RECOMBINANT - INJECTION

C1-ESTERASE INHIBITOR (TREATMENT), RECOMBINANT - INJECTION

PHONETIC PRONUNCIATION:

COMMON BRAND NAME(S): Ruconest

GENERIC NAME(S): C1 esterase inhibitor, recombinant

Uses

USES: This medication is used to treat the swelling problems caused by a certain immune disease passed down through families (hereditary angioedema-HAE). HAE is caused by low levels or improper function of a natural substance produced by the body (C1-esterase inhibitor). Symptoms such as rapid swelling of the hands, feet, limbs, face, tongue, or throat can occur. Swelling of the intestinal tract may cause symptoms such as abdominal cramps, diarrhea, or vomiting. Attacks of swelling may occur without reason. However, anxiety, stress, sickness, and surgery may trigger attacks in some people. This medication works by increasing the level of C1-esterase inhibitor to help treat attacks of sudden swelling due to hereditary angioedema.


How to use C1-ESTERASE INHIBITOR (TREATMENT), RECOMBINANT - INJECTION

HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start using C1-esterase inhibitor and each time you get a refill. If you have any questions, ask your doctor or pharmacist. This medication is given by injection into a vein, at the first signs of an HAE attack, as directed by your doctor. The dosage is based on weight and your medical condition. Do not use more than 4,200 international units per dose. Do not use more than 2 doses in a 24-hour period. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. The solution is normally clear and colorless. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. If the medication and the solution used to mix it have been refrigerated, bring both to room temperature before combining. Learn how to store and discard medical supplies safely. After giving yourself a dose of this medication, you should get medical help right away for follow-up treatment. Tell your doctor if your condition does not improve or if it worsens.

Side Effects

SIDE EFFECTS: Headache may occur. If this effect persists or worsens, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may increase the risk for blood clots (such as pulmonary embolism, stroke, heart attack, deep vein thrombosis). You may be at increased risk for blood clots if you have a history of blood clots, heart/blood vessel disease, heart failure, stroke, or if you are immobile (possibly for reasons like being on a very long plane flight or being bedridden). If you use estrogen-containing products, these may also increase your risk. Before using this medication, if you have any of these conditions tell your doctor or pharmacist. Serious blood clots may cause pulmonary embolism, stroke, heart attack, or deep vein thrombosis. Get medical help right away if you have any of these side effects: shortness of breath/rapid breathing, chest/jaw/left arm pain, unusual sweating, confusion, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, sudden/severe headaches, weakness on one side of the body, sudden vision changes. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before using C1-esterase inhibitor, tell your doctor or pharmacist if you are allergic to it; or to rabbits or rabbit-based products; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood clots (such as in the lungs, legs). Before traveling, talk to your doctor to make sure you have enough of this medication. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Images

RUCONEST 2,100 UNIT VIAL
RUCONEST 2,100 UNIT VIAL
color
colorless
shape
imprint
RUCONEST 2,100 UNIT VIAL
RUCONEST 2,100 UNIT VIAL
color
colorless
shape
imprint

Reviews

No Reviews Yet


Faq for C1-ESTERASE INHIBITOR (TREATMENT), RECOMBINANT - INJECTION

C1-esterase inhibitor (treatment), recombinant - injection is a medication used to treat hereditary angioedema (HAE), a rare genetic disorder that causes recurrent episodes of swelling in various parts of the body.

C1-esterase inhibitor helps to regulate the production of C1-esterase inhibitor protein in the body, which is deficient in patients with HAE. By increasing the levels of this protein, the medication helps to prevent or reduce the severity of swelling attacks.

C1-esterase inhibitor (treatment), recombinant - injection is administered as an injection under the skin (subcutaneously). The injection is typically performed by a healthcare professional, but some patients may be trained to self-administer the medication.

Common side effects of C1-esterase inhibitor (treatment), recombinant - injection may include headache, nausea, diarrhea, fatigue, fever, injection site reactions (such as pain or swelling), and dizziness. These side effects are usually mild and temporary.

The frequency of C1-esterase inhibitor (treatment), recombinant - injection depends on your specific treatment plan and the severity of your HAE. Your healthcare provider will determine the appropriate dosing schedule for you.

It is important to discuss the use of C1-esterase inhibitor (treatment), recombinant - injection with your healthcare provider if you are pregnant or breastfeeding. While there is limited data on its safety during these periods, the potential benefits and risks should be evaluated.

C1-esterase inhibitor (treatment), recombinant - injection is not known to have significant interactions with other medications. However, it is always important to inform your healthcare provider about all the medications, vitamins, and supplements you are taking to minimize any potential interactions.

The onset of action of C1-esterase inhibitor (treatment), recombinant - injection varies among individuals. Some patients may experience relief from symptoms within minutes to hours after the injection, while others may take longer to respond.

C1-esterase inhibitor (treatment), recombinant - injection does not cure HAE but helps to manage the symptoms and reduce the frequency and severity of swelling attacks. It is a long-term treatment that needs to be continued as prescribed by your healthcare provider.

C1-ESTERASE INHIBITOR (TREATMENT), RECOMBINANT - INJECTION Pricing Page Get Discount Coupon


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.