BETRIXABAN - ORAL

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BETRIXABAN - ORAL

PHONETIC PRONUNCIATION: (be-TRIX-a-ban)

COMMON BRAND NAME(S): Bevyxxa

GENERIC NAME(S): betrixaban maleate

Uses

USES: Betrixaban is used to prevent serious blood clots from forming in people who are in the hospital for a serious illness and at an increased risk for blood clots (such as by being bedridden). Betrixaban is an anticoagulant that works by blocking certain clotting proteins in your blood.


How to use BETRIXABAN - ORAL

HOW TO USE: See also Warning section. Read the Medication Guide provided by your pharmacist before you start taking betrixaban and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with food as directed by your doctor, usually once daily. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Side Effects

SIDE EFFECTS: See also Warning section. Easy bruising or minor bleeding (such as nosebleed, bleeding from cuts) may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication can cause serious bleeding if it affects your blood clotting proteins too much. Tell your doctor right away if you have any signs of serious bleeding, including: unusual pain/swelling/discomfort, unusual bruising, bleeding from cuts or gums that doesn't stop, nosebleeds that don't stop or happen often, unusually heavy/lasting menstrual flow, pink/dark urine, coughing up blood, vomit that is bloody or looks like coffee grounds, severe headache, dizziness/fainting, tiredness/weakness that is unusual or doesn't go away, bloody/black/tarry stools, difficulty swallowing. Get medical help right away if you have any signs of very serious bleeding, including: sudden vision changes, confusion, trouble speaking, weakness on one side of the body. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

PRECAUTIONS: Before taking betrixaban, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, bleeding problems (such as bleeding of the stomach/intestines, bleeding in the brain), blood disorders (such as anemia, hemophilia, thrombocytopenia), recent major injury/surgery, frequent falls/injuries, stroke. Before having surgery or any medical/dental procedures (especially spinal puncture or spinal/epidural anesthesia), tell your doctor or dentist that you are taking this medication and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor or dentist may tell you to stop taking betrixaban before your surgery. Ask for specific instructions about stopping or starting this medication. This medication may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages. Ask your doctor or pharmacist about how much alcohol you may safely drink. This medication can cause bleeding. To lower the chance of getting cut, bruised, or injured, use great caution with sharp objects like safety razors and nail cutters. Use an electric razor when shaving and a soft toothbrush when brushing your teeth. Avoid activities such as contact sports. If you fall or injure yourself, especially if you hit your head, contact your doctor right away. Your doctor may need to check you for hidden bleeding that could be serious. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor before using this medication. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug are: mifepristone, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, "blood thinners" such as warfarin/dabigatran), certain antidepressants (including SSRIs such as fluoxetine, SNRIs such as desvenlafaxine/venlafaxine). Aspirin can increase the risk of bleeding when used with this medication. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

Overdose

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: bloody/black/tarry stools, pink/dark urine, bleeding that is unusual or doesn't stop.

Images

BEVYXXA 80 MG CAPSULE
BEVYXXA 80 MG CAPSULE
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PTLA, 80
BEVYXXA 40 MG CAPSULE
BEVYXXA 40 MG CAPSULE
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PTLA, 40

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Faq for BETRIXABAN - ORAL

Betrixaban is an oral anticoagulant medication used to prevent blood clots in adults who are at risk of developing deep vein thrombosis (DVT) and pulmonary embolism (PE) after a hospital stay for an acute medical illness.

Betrixaban belongs to a class of medications called direct factor Xa inhibitors. It works by inhibiting the action of factor Xa, which plays a crucial role in the process of blood clot formation. By inhibiting factor Xa, Betrixaban helps to prevent blood clots from forming.

The recommended dosage of Betrixaban for most patients is an initial intake of 160 mg on the first day, followed by a maintenance dose of 80 mg once daily for the duration of the prescribed treatment.

Common side effects of Betrixaban may include bruising, nosebleeds, headache, dizziness, and bleeding gums. However, it is essential to notify your healthcare provider immediately if you experience any signs of serious bleeding, such as black or bloody stools, coughing up blood, or severe headaches.

It is important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications may interact with Betrixaban, increasing the risk of bleeding or affecting its effectiveness. Your healthcare provider will evaluate any potential drug interactions before prescribing Betrixaban.

The duration of Betrixaban treatment varies depending on the individual's medical condition and overall risk factors. Typically, treatment with Betrixaban lasts for 35 to 42 days.

There are no specific dietary restrictions while taking Betrixaban. However, it is important to avoid excessive consumption of alcohol, as it may increase the risk of bleeding.

If you miss a dose of Betrixaban, take it as soon as you remember and continue with your regular dosing schedule. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue as usual. Do not double the dose to make up for a missed one.

Betrixaban has not been studied extensively in pregnant women or breastfeeding mothers. It is recommended to consult with your healthcare provider before using Betrixaban if you are pregnant, planning to become pregnant, or breastfeeding.

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Warning

WARNING: Do not stop taking betrixaban unless directed by your doctor. If you stop taking this medication early, you have a higher risk of forming a serious blood clot (such as a stroke, blood clot in the legs/lungs). Your doctor may direct you to take a different "blood thinning" or antiplatelet medication to reduce your risk. Get medical help right away if you have weakness on one side of the body, trouble speaking, sudden vision changes, confusion, chest pain, trouble breathing, or pain/warmth/swelling in the legs. People taking this medication may bleed near the spinal cord after certain spinal procedures. Bleeding in this area can cause paralysis that lasts a long time or could become permanent. Ask your doctor about the benefits and risks before any spinal procedure. The risk of bleeding may be higher if you have a deformed spine, or have had spinal procedures/surgery before (such as epidural catheter placement, difficult epidural/spinal puncture), or are taking other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin/enoxaparin, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen). Tell your doctor right away if you notice symptoms such as back pain, leg numbness/tingling/weakness, loss of control of the bowels or bladder (incontinence).


Disclaimer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.